Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function

Metabolic reprogramming during neuronal differentiation

(2016) M Agostini et al.   CELL DEATH AND DIFFERENTIATION

Protective roles of melatonin in central nervous system diseases by regulation of neural stem cells

(2016) Xin Yu et al.   CELL PROLIFERATION

Effects of Aging on Neural Stem/Progenitor Cells and Oligodendrocyte Precursor Cells after Focal Cerebral Ischemia in Spontaneously Hypertensive Rats

(2016) Anna C. Liang et al.   CELL TRANSPLANTATION

Melatonin Increases Oligodendrocyte Differentiation in Cultured Neural Stem Cells

(2016) Majid Ghareghani et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's disease

(2016) M.J. Lelos et al.   EXPERIMENTAL NEUROLOGY

Combination of melatonin and Wnt-4 promotes neural cell differentiation in bovine amniotic epithelial cells and recovery from spinal cord injury

(2016) Yuhua Gao et al.   JOURNAL OF PINEAL RESEARCH

Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network

(2016) María E. Díaz-Casado et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network

(2016) Carolina Doerrier et al.   MITOCHONDRION

The Adult Ventricular–Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis

(2016) Daniel A. Lim et al.   Cold Spring Harbor Perspectives in Biology

A Compendium of Preparation and Application of Stem Cells in Parkinson's Disease: Current Status and Future Prospects

(2016) Yan Shen et al.   Frontiers in Aging Neuroscience

Mosaic Subventricular Origins of Forebrain Oligodendrogenesis

(2016) Kasum Azim et al.   Frontiers in Neuroscience

Transplantation of Defined Populations of Differentiated Human Neural Stem Cell Progeny

(2016) Jeff M. Fortin et al.   Scientific Reports

Resistance of glia-like central and peripheral neural stem cells to genetically induced mitochondrial dysfunction--differential effects on neurogenesis

(2015) B. Diaz-Castro et al.   EMBO REPORTS

Transplantation of Human Neural Stem Cells in a Parkinsonian Model Exerts Neuroprotection via Regulation of the Host Microenvironment

(2015) Fu-Xing Zuo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry

(2015) Carolina Doerrier et al.   LIFE SCIENCES

Molecular aspects of melatonin (MLT)-mediated therapeutic effects

(2015) Hardeep Singh Tuli et al.   LIFE SCIENCES

Biomarkers of Parkinson’s disease: Present and future

(2015) Diane B. Miller et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Human neural stem cells alleviate Alzheimer-like pathology in a mouse model

(2015) Il-Shin Lee et al.   Molecular Neurodegeneration

Melatonin: Physiological effects in humans

(2015) B. Claustrat et al.   NEUROCHIRURGIE

Mitochondria

(2015) Joana M. Xavier et al.   NEUROSCIENTIST

Dynamin-related protein 1 controls the migration and neuronal differentiation of subventricular zone-derived neural progenitor cells

(2015) Hyun Jung Kim et al.   Scientific Reports

Current states of endogenous stem cells in adult spinal cord

(2014) Yu Qin et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Melatonin enhances adult rat hippocampal progenitor cell proliferation via ERK signaling pathway through melatonin receptor

(2014) C. Tocharus et al.   NEUROSCIENCE

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Melatonin-mitochondria Interplay in Health and Disease

(2012) Dario Acuna Castroviejo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Mitochondrial DNA and inflammatory diseases

(2011) Germaine Escames et al.   HUMAN GENETICS

Melatonin promotes proliferation and differentiation of neural stem cells subjected to hypoxia in vitro

(2011) Jie Fu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse

(2011) Yoelvis García-Mesa et al.   NEUROBIOLOGY OF AGING

Brain Regeneration in Physiology and Pathology: The Immune Signature Driving Therapeutic Plasticity of Neural Stem Cells

(2011) Gianvito Martino et al.   PHYSIOLOGICAL REVIEWS

In Vitro Characterization of Trophic Factor Expression in Neural Precursor Cells

(2011) Gregory W.J. Hawryluk et al.   STEM CELLS AND DEVELOPMENT

Melatonin signaling and cell protection function

(2010) Francesca Luchetti et al.   FASEB JOURNAL

Melatonin increases proliferation of cultured neural stem cells obtained from adult mouse subventricular zone

(2010) Areechun Sotthibundhu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin treatment normalizes plasma pro-inflammatory cytokines and nitrosative/oxidative stress in patients suffering from Duchenne muscular dystrophy

(2010) Mariam Chahbouni et al.   JOURNAL OF PINEAL RESEARCH

Metabolic oxidation regulates embryonic stem cell differentiation

(2010) Oscar Yanes et al.   Nature Chemical Biology

IGF-1 Reduces BACE-1 Expression in PC12 Cells via Activation of PI3-K/Akt and MAPK/ERK1/2 Signaling Pathways

(2010) Hua Zhang et al.   NEUROCHEMICAL RESEARCH

Treatment of CoQ10 Deficient Fibroblasts with Ubiquinone, CoQ Analogs, and Vitamin C: Time- and Compound-Dependent Effects

(2010) Luis C. López et al.   PLoS One

Upregulation of mitochondrial function and antioxidant defense in the differentiation of stem cells

(2009) Chien-Tsun Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of neuron mitochondrial biogenesis and relevance to brain health

(2009) Isaac G. Onyango et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Melatonin and its brain metabolite N1-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice

(2009) Víctor Tapias et al.   JOURNAL OF NEUROSCIENCE RESEARCH

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Characterization of Adult Neural Stem Cells and Their Relation to Brain Tumors

(2008) Erica L. Jackson et al.   CELLS TISSUES ORGANS

Unbalanced deoxynucleotide pools cause mitochondrial DNA instability in thymidine phosphorylase-deficient mice

(2008) Luis C. López et al.   HUMAN MOLECULAR GENETICS

Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells

(2008) Rohita Sharma et al.   JOURNAL OF PINEAL RESEARCH

Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production

(2008) Ana López et al.   JOURNAL OF PINEAL RESEARCH

Melatonin prevents amyloid protofibrillar induced oxidative imbalance and biogenic amine catabolism

(2008) Masilamoni J. Gunasingh et al.   LIFE SCIENCES