Non-coding RNAs in cardiac hypertrophy

Lessons from reverse-genetic studies of lncRNAs

(2016) Shinichi Nakagawa   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MicroRNAs in Cardiovascular Disease

(2016) Nikolaos Papageorgiou et al.   Cardiology in Review

Extracellular matrix-mediated cellular communication in the heart

(2016) Iñigo Valiente-Alandi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Physiological and pathological cardiac hypertrophy

(2016) Ippei Shimizu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Epidemiology and aetiology of heart failure

(2016) Boback Ziaeian et al.   Nature Reviews Cardiology

The biogenesis and emerging roles of circular RNAs

(2016) Ling-Ling Chen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long noncoding RNA Chast promotes cardiac remodeling

(2016) Janika Viereck et al.   Science Translational Medicine

Circular RNA Expression: Its Potential Regulation and Function

(2016) Julia Salzman   TRENDS IN GENETICS

Circular RNA: A new star of noncoding RNAs

(2015) Shibin Qu et al.   CANCER LETTERS

TGF  Triggers miR-143/145 Transfer From Smooth Muscle Cells to Endothelial Cells, Thereby Modulating Vessel Stabilization

(2015) M. Climent et al.   CIRCULATION RESEARCH

Blood-based microRNA signatures differentiate various forms of cardiac hypertrophy

(2015) Anselm A. Derda et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases

(2015) Krystal Archer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Long noncoding RNAs in cardiac development and ageing

(2015)   Nature Reviews Cardiology

Glucose Starvation in Cardiomyocytes Enhances Exosome Secretion and Promotes Angiogenesis in Endothelial Cells

(2015) Nahuel A. Garcia et al.   PLoS One

HypoxamiRs: regulators of cardiac hypoxia and energy metabolism

(2015) Hamid el Azzouzi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Emerging role of microRNAs in lipid metabolism

(2015) Zhihong Yang et al.   Acta Pharmaceutica Sinica B

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support

(2014) Kai-Chien Yang et al.   CIRCULATION

The Long Noncoding RNA CHRF Regulates Cardiac Hypertrophy by Targeting miR-489

(2014) Kun Wang et al.   CIRCULATION RESEARCH

MicroRNA-133 Modulates the β 1 -Adrenergic Receptor Transduction Cascade

(2014) Alessandra Castaldi et al.   CIRCULATION RESEARCH

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

(2014) Slava Epelman et al.   IMMUNITY

Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

(2014) Claudia Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

miR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 signaling

(2014) Yang Zhang et al.   MOLECULAR THERAPY

A long noncoding RNA protects the heart from pathological hypertrophy

(2014) Pei Han et al.   NATURE

miR-181c Regulates the Mitochondrial Genome, Bioenergetics, and Propensity for Heart Failure In Vivo

(2014) Samarjit Das et al.   PLoS One

Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs

(2014) S. J. Matkovich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment

(2013) Carla A. Klattenhoff et al.   CELL

The Hypoxia-Inducible MicroRNA Cluster miR-199a∼214 Targets Myocardial PPARδ and Impairs Mitochondrial Fatty Acid Oxidation

(2013) Hamid el Azzouzi et al.   Cell Metabolism

MicroRNA-22 Downregulation by Atorvastatin in a Mouse Model of Cardiac Hypertrophy: a new Mechanism for Antihypertrophic Intervention

(2013) Yingfeng Tu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure

(2013) Stephane Heymans et al.   CIRCULATION

Extracellular Matrix Secretion by Cardiac Fibroblasts

(2013) Mélanie Abonnenc et al.   CIRCULATION RESEARCH

MicroRNA-22 Regulates Cardiac Hypertrophy and Remodeling in Response to Stress

(2013) Zhan-Peng Huang et al.   CIRCULATION RESEARCH

The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

(2013) Phillip Grote et al.   DEVELOPMENTAL CELL

MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension

(2013) R. S. Friese et al.   HUMAN MOLECULAR GENETICS

MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy

(2013) Julie Halkein et al.   JOURNAL OF CLINICAL INVESTIGATION

Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy

(2013) Roberta Roncarati et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

A Deep Sequencing Approach to Uncover the miRNOME in the Human Heart

(2013) Stefanos Leptidis et al.   PLoS One

Exosomal Signaling during Hypoxia Mediates Microvascular Endothelial Cell Migration and Vasculogenesis

(2013) Carlos Salomon et al.   PLoS One

A Circuitous Route to Noncoding RNA

(2013) J. E. Wilusz et al.   SCIENCE

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Targeted Deletion of MicroRNA-22 Promotes Stress-Induced Cardiac Dilation and Contractile Dysfunction

(2012) Priyatansh Gurha et al.   CIRCULATION

Direct and Indirect Involvement of MicroRNA-499 in Clinical and Experimental Cardiomyopathy

(2012) Scot J. Matkovich et al.   CIRCULATION RESEARCH

A Novel Cardiomyocyte-enriched MicroRNA, miR-378, Targets Insulin-like Growth Factor 1 Receptor

(2012) Ivana Knezevic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Circulating Level of FABP3 Is an Indirect Biomarker of MicroRNA-1

(2012) Francesca Varrone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiomyocyte Microvesicles Contain DNA/RNA and Convey Biological Messages to Target Cells

(2012) Anders Waldenström et al.   PLoS One

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy

(2012) Ahmet Ucar et al.   Nature Communications

Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice

(2011) Jian Wang et al.   CELL RESEARCH

Chromatin Remodeling in Cardiovascular Development and Physiology

(2011) Pei Han et al.   CIRCULATION RESEARCH

Analysis of Transcriptome Complexity Through RNA Sequencing in Normal and Failing Murine Hearts

(2011) Jae-Hyung Lee et al.   CIRCULATION RESEARCH

Attenuation of MicroRNA-22 derepressed PTEN to effectively protect rat cardiomyocytes from hypertrophy

(2011) Xu-Dong Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes

(2011) Claudia Jentzsch et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

miR-210: The Master Hypoxamir

(2011) YUK C. CHAN et al.   MICROCIRCULATION

Left Ventricular Remodeling in Heart Failure

(2011) Marvin A. Konstam et al.   JACC-Cardiovascular Imaging

The microRNA miR-696 regulates PGC-1α in mouse skeletal muscle in response to physical activity

(2010) Wataru Aoi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease

(2010) S. Hu et al.   CIRCULATION

Molecular Pathways Underlying Cardiac Remodeling During Pathophysiological Stimulation

(2010) Izhak Kehat et al.   CIRCULATION

Thioredoxin 1 Negatively Regulates Angiotensin II–Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7

(2010) Yanfei Yang et al.   CIRCULATION RESEARCH

Circulating MicroRNA-208b and MicroRNA-499 Reflect Myocardial Damage in Cardiovascular Disease

(2010) Maarten F. Corsten et al.   Circulation-Cardiovascular Genetics

Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans

(2010) Guo-Kun Wang et al.   EUROPEAN HEART JOURNAL

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutic targeting of innate immunity in the failing heart

(2010) Veli K. Topkara et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling

(2010) Paula A. da Costa Martins et al.   NATURE CELL BIOLOGY

Reciprocal Regulation of Myocardial microRNAs and Messenger RNA in Human Cardiomyopathy and Reversal of the microRNA Signature by Biomechanical Support

(2009) Scot J. Matkovich et al.   CIRCULATION

Reciprocal Regulation of MicroRNA-1 and Insulin-Like Growth Factor-1 Signal Transduction Cascade in Cardiac and Skeletal Muscle in Physiological and Pathological Conditions

(2009) Leonardo Elia et al.   CIRCULATION

MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts

(2009) Scot J. Matkovich et al.   CIRCULATION RESEARCH

MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice

(2009) Thomas E. Callis et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-21 protects against the H2O2-induced injury on cardiac myocytes via its target gene PDCD4

(2009) Yunhui Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Ionizing Radiation-Induced Oxidative Stress Alters miRNA Expression

(2009) Nicole L. Simone et al.   PLoS One

miR-133 and miR-30 Regulate Connective Tissue Growth Factor

(2008) Rudy F. Duisters et al.   CIRCULATION RESEARCH

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

(2008) E. van Rooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA