Mitochondrial proteostasis as a shared characteristic of slowed aging: the importance of considering cell proliferation

Skeletal muscle insulin resistance: role of mitochondria and other ROS sources

(2017) Sergio Di Meo et al.   JOURNAL OF ENDOCRINOLOGY

The Aging Cardiovascular System

(2017) Francesco Paneni et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mitochondria and mitochondria-induced signalling molecules as longevity determinants

(2017) Giuseppina Rose et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

(2017) Annika Höhn et al.   Redox Biology

The Unfolded Protein Response: At the Intersection between Endoplasmic Reticulum Function and Mitochondrial Bioenergetics

(2017) Amado Carreras-Sureda et al.   Frontiers in Oncology

Protein synthesis as an integral quality control mechanism during ageing

(2015) Nikolaos Charmpilas et al.   AGEING RESEARCH REVIEWS

Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects

(2015) Pabalu P. Karunadharma et al.   AGING CELL

Long-lived Snell dwarf mice display increased proteostatic mechanisms that are not dependent on decreased mTORC1 activity

(2015) Joshua C. Drake et al.   AGING CELL

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Modeling the contribution of individual proteins to mixed skeletal muscle protein synthetic rates over increasing periods of label incorporation

(2015) Benjamin F. Miller et al.   JOURNAL OF APPLIED PHYSIOLOGY

Reconsidering the Role of Mitochondria in Aging

(2015) Marta Gonzalez-Freire et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Proteostasis and aging

(2015) Susmita Kaushik et al.   NATURE MEDICINE

The measurement of protein synthesis for assessing proteostasis in studies of slowed aging

(2014) Benjamin F. Miller et al.   AGEING RESEARCH REVIEWS

Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart

(2014) Dao-Fu Dai et al.   AGING CELL

Long-lived crowded-litter mice have an age-dependent increase in protein synthesis to DNA synthesis ratio and mTORC1 substrate phosphorylation

(2014) Joshua C. Drake et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Geroscience: Linking Aging to Chronic Disease

(2014) Brian K. Kennedy et al.   CELL

Assessment of Mitochondrial Biogenesis and mTORC1 Signaling During Chronic Rapamycin Feeding in Male and Female Mice

(2013) Joshua C. Drake et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Chronic Caloric Restriction Preserves Mitochondrial Function in Senescence without Increasing Mitochondrial Biogenesis

(2012) Ian R. Lanza et al.   Cell Metabolism

Calorie Restriction Does Not Increase Short-term or Long-term Protein Synthesis

(2012) B. F. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The Effect of Long Term Calorie Restriction onin VivoHepatic Proteostatis: A Novel Combination of Dynamic and Quantitative Proteomics

(2012) John C. Price et al.   MOLECULAR & CELLULAR PROTEOMICS

A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction

(2011) Benjamin F. Miller et al.   AGING CELL

A perspective on the determination of mitochondrial biogenesis

(2011) Benjamin F. Miller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging

(2010) Pankaj Kapahi et al.   Cell Metabolism

Does calorie restriction induce mitochondrial biogenesis? A reevaluation

(2010) Chad R. Hancock et al.   FASEB JOURNAL

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Muscle mitochondrial changes with aging and exercise

(2008) Ian R Lanza et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Ageing and the regulation of protein synthesis: a balancing act?

(2008) Nektarios Tavernarakis   TRENDS IN CELL BIOLOGY