Limitations of polyethylene glycol-induced precipitation as predictive tool for protein solubility during formulation development

Mechanism of Reversible Self-Association of a Monoclonal Antibody: Role of Electrostatic and Hydrophobic Interactions

(2015) Reza Esfandiary et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Opalescence in Monoclonal Antibody Solutions and Its Correlation with Intermolecular Interactions in Dilute and Concentrated Solutions

(2015) Ashlesha S. Raut et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Application of a PEG precipitation method for solubility screening: A tool for developing high protein concentration formulations

(2013) Li Li et al.   PROTEIN SCIENCE

Impact of short range hydrophobic interactions and long range electrostatic forces on the aggregation kinetics of a monoclonal antibody and a dual-variable domain immunoglobulin at low and high concentrations

(2011) Vineet Kumar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Application of a High-Throughput Screening Procedure with PEG-Induced Precipitation to Compare Relative Protein Solubility During Formulation Development with IgG1 Monoclonal Antibodies

(2010) Todd J. Gibson et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Protein aggregation: more than just fibrils

(2009) Mark R.H. Krebs et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Specific interactions in high concentration antibody solutions resulting in high viscosity

(2009) Sandeep Yadav et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Nature and consequences of protein–protein interactions in high protein concentration solutions

(2008) Atul Saluja et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Measuring and Increasing Protein Solubility

(2008) Saul R. Trevino et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Shaken, Not Stirred: Mechanical Stress Testing of an IgG1 Antibody

(2008) Sylvia Kiese et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Protein Phase Behavior in Aqueous Solutions: Crystallization, Liquid-Liquid Phase Separation, Gels, and Aggregates

(2007) André C. Dumetz et al.   BIOPHYSICAL JOURNAL