Challenges in longitudinal exposure-response modeling of data from complex study designs: a case study of modeling CDAI score for ustekinumab in patients with Crohn’s disease

Evaluation of estimation, prediction and inference for autocorrelated latent variable modeling of binary data—a simulation study

(2016) Matthew M. Hutmacher   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease

(2016) Brian G. Feagan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pattern Recognition in Pharmacodynamic Data Analysis

(2015) Johan Gabrielsson et al.   AAPS Journal

Improvement in latent variable indirect response joint modeling of a continuous and a categorical clinical endpoint in rheumatoid arthritis

(2015) Chuanpu Hu et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease

(2012) William J. Sandborn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Informative dropout modeling of longitudinal ordered categorical data and model validation: application to exposure–response modeling of physician’s global assessment score for ustekinumab in patients with psoriasis

(2011) Chuanpu Hu et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

A Pharmacodynamic Markov Mixed-Effects Model for Determining the Effect of Exposure to Certolizumab Pegol on the ACR20 Score in Patients With Rheumatoid Arthritis

(2009) B D Lacroix et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Population-Based Exposure-Efficacy Modeling of Ustekinumab in Patients With Moderate to Severe Plaque Psoriasis

(2009) Honghui Zhou et al.   JOURNAL OF CLINICAL PHARMACOLOGY