Metabolic Activation of Cholestatic Drug-Induced Bile Acid-Dependent Toxicity in Human Sandwich-Cultured Hepatocytes

Title
Metabolic Activation of Cholestatic Drug-Induced Bile Acid-Dependent Toxicity in Human Sandwich-Cultured Hepatocytes
Authors
Keywords
CYP enzyme, hepatocyte, bile acid transporter, toxicity, in vitro, model
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 106, Issue 9, Pages 2509-2514
Publisher
Elsevier BV
Online
2017-04-30
DOI
10.1016/j.xphs.2017.04.050

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