Pretreatment With Rifampicin and Tyrosine Kinase Inhibitor Dasatinib Potentiates the Inhibitory Effects Toward OATP1B1- and OATP1B3-Mediated Transport

Published 2017 View Full Article

Title

Pretreatment With Rifampicin and Tyrosine Kinase Inhibitor Dasatinib Potentiates the Inhibitory Effects Toward OATP1B1- and OATP1B3-Mediated Transport

Authors

Keywords

drug transport, drug interactions, organic anion-transporting polypeptide transporters, hepatocytes, hepatic transport, pharmacokinetics, physiologically based pharmacokinetic modeling

Journal

JOURNAL OF PHARMACEUTICAL SCIENCES

Volume 106, Issue 8, Pages 2123-2135

Publisher

Elsevier BV

Online

2017-04-01

DOI

10.1016/j.xphs.2017.03.022

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