Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy

Title
Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy
Authors
Keywords
proteins, excipients, surfactants, stability, protein aggregation, protein structure, protein formulation, stabilization, protein binding, physical characterization
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 106, Issue 12, Pages 3486-3498
Publisher
Elsevier BV
Online
2017-08-24
DOI
10.1016/j.xphs.2017.08.011

Ask authors/readers for more resources

Reprint

Contact the author

Discover Peeref hubs

Discuss science. Find collaborators. Network.

Join a conversation

Become a Peeref-certified reviewer

The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.

Get Started