LC–MS/MS method for the simultaneous determination of Lys-MCC-DM1, MCC-DM1 and DM1 as potential intracellular catabolites of the antibody-drug conjugate trastuzumab emtansine (T-DM1)

Title
LC–MS/MS method for the simultaneous determination of Lys-MCC-DM1, MCC-DM1 and DM1 as potential intracellular catabolites of the antibody-drug conjugate trastuzumab emtansine (T-DM1)
Authors
Keywords
Antibody-drug conjugate, T-DM1, LC–MS/MS, Catabolites
Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 137, Issue -, Pages 170-177
Publisher
Elsevier BV
Online
2017-01-13
DOI
10.1016/j.jpba.2017.01.011

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