Article
Nutrition & Dietetics
Wojciech Roczniak, Agnieszka Szymlak, Bogdan Mazur, Agata Chobot, Malgorzata Stojewska, Joanna Oswiecimska
Summary: This study assessed the nutritional status and serum concentrations of adipokines in children with irritable bowel syndrome (IBS) and healthy controls. The results showed significant differences in serum chemerin and omentin-1 concentrations between IBS patients and healthy children. These adipokines could be used as IBS biomarkers as they demonstrate good specificity and moderate sensitivity.
Article
Gastroenterology & Hepatology
Giovanni Marasco, Cesare Cremon, Maria Raffaella Barbaro, Giulia Cacciari, Francesca Falangone, Anna Kagramanova, Dmitry Bordin, Vasile Drug, Egidia Miftode, Pietro Fusaroli, Salem Youssef Mohamed, Chiara Ricci, Massimo Bellini, Mohammed Masudur Rahman, Luigi Melcarne, Javier Santos, Beatriz Lobo, Serhat Bor, Suna Yapali, Deniz Akyol, Ferdane Pirincci Sapmaz, Yonca Yilmaz Urun, Tugce Eskazan, Altay Celebi, Huseyin Kacmaz, Berat Ebik, Hatice Cilem Binicier, Mehmet Sait Bugdayci, Munkhtsetseg Banzragch Yagci, Husnu Pullukcu, Berrin Yalinbas Kaya, Ali Tureyen, Ibrahim Hatemi, Elif Sitre Koc, Goktug Sirin, Ali Riza Caliskan, Goksel Bengi, Esra Ergun Alis, Snezana Lukic, Meri Trajkovska, Keren Hod, Dan Dumitrascu, Antonello Pietrangelo, Elena Corradini, Magnus Simren, Jessica Sjoelund, Navkiran Tornkvist, Uday C. Ghoshal, Olga Kolokolnikova, Antonio Colecchia, Jordi Serra, Giovanni Maconi, Roberto De Giorgio, Silvio Danese, Piero Portincasa, Antonio Di Sabatino, Marcello Maggio, Elena Philippou, Yeong Yeh Lee, Daniele Salvi, Alessandro Venturi, Claudio Borghi, Marco Zoli, Paolo Gionchetti, Pierluigi Viale, Vincenzo Stanghellini, Giovanni Barbara
Summary: This study aimed to evaluate the prevalence of gastrointestinal symptoms and post-COVID-19 disorders of gut-brain interaction among hospitalized patients with SARS-CoV-2 infection. The results showed that patients with COVID-19 had higher rates of gastrointestinal symptoms on hospital admission and lower rates of constipation and hard stools at 12 months post-infection compared to the control group. Additionally, the rate of irritable bowel syndrome was significantly higher in patients with COVID-19 than in controls.
Review
Pediatrics
Elvira Ingrid Levy, Charlotte De Geyter, Abdelhalim Ouald Chaib, Berthold Albert Aman, Badriul Hegar, Yvan Vandenplas
Summary: There are limited randomized controlled trials on managing pediatric IBS, with most intervention trials targeting changes to the gastrointestinal microbiome. Heterogeneity in study designs and outcomes make it difficult to formulate recommendations. Insufficient evidence exists to recommend therapeutic interventions in pediatric IBS, despite the association with dysbiosis. More prospective trials are needed.
Article
Gastroenterology & Hepatology
Michael Camilleri, Guy Boeckxstaens
Summary: This article evaluates the evidence that targeted pathophysiological mechanisms and customized treatments can be an alternative approach to treating patients with irritable bowel syndrome (IBS). The authors conducted a literature review on the mechanisms and treatments of IBS, identifying various noninvasive clinical tests that can assess the underlying mechanisms responsible for symptom generation. These mechanisms include rectal evacuation disorders, abnormal transit, visceral hypersensitivity or hypervigilance, bile acid diarrhea, sugar intolerances, barrier dysfunction, the microbiome, immune activation, and chemicals released by these mechanisms. The authors also recognized the basic molecular mechanisms contributing to these pathophysiologies, offering opportunities for interventions with medications targeted at specific food components, receptors, and potentially the microbiome. Although the evidence supporting interventions for each mechanism varies, the current state-of-the-art allows for a shift from symptom-based treatment to individualized treatment guided by pathophysiology and clinically identified biomarkers.
Review
Medicine, General & Internal
Mihaela Fadgyas Stanculete, Abdulrahman Ismaiel, Stefan-Lucian Popa, Octavia Oana Capatina
Summary: Irritable bowel syndrome (IBS) is a disorder characterized by altered gut-brain interaction and dysfunction of the brain-gut-microbiota axis. Prior studies have shown significant impairments in the health-related quality of life of patients with IBS. Resilience, as a psychosocial ability, plays a crucial role in promoting health and enhancing stress response.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Nutrition & Dietetics
Daniela Pop, Radu Samuel Pop, Dorin Farcau
Summary: This paper discusses the benefits of peppermint oil, STW5, psyllium fiber, Curcuma, ginger, and other herbal medicines in pediatric patients with irritable bowel syndrome, based on findings in the current literature.
Review
Nutrition & Dietetics
Robin Spiller
Summary: IBS is strongly influenced by diet, but identifying specific food intolerances is difficult due to the complexities of diet. Rapidly fermented carbohydrates and gut-specific mast cell activation may cause symptoms in IBS patients. More research is needed to fully understand the mechanisms of food intolerances and improve personalized medicine approaches to diet in IBS.
Article
Gastroenterology & Hepatology
Qi Su, Hein M. Tun, Qin Liu, Yun Kit Yeoh, Joyce Wing Yan Mak, Francis K. L. Chan, Siew C. Ng
Summary: This study examined the association between gut microbiota and Irritable bowel syndrome (IBS) subtypes, and found that there are distinct differences in microbiota composition among different IBS subtypes. The microbial diversity is significantly reduced in IBS-D and IBS-U, but not in IBS-C. The study also identified microbial signatures associated with depression in IBS patients. Factors such as gender, age, and dietary patterns have significant effects on gut microbiota in different IBS subtypes. These findings emphasize the importance of personalized gut microbiome modulation approaches for optimal therapeutic effects in different subtypes of IBS.
Review
Immunology
Ying Gao, Peilun Ding, Junmin Wang, Caiyun Zhang, Guang Ji, Tao Wu
Summary: "Application of Metabolomics in Irritable Bowel Syndrome: A Review" provides an updated overview of metabolomics studies related to irritable bowel syndrome (IBS) in the past 5 years, including clinical studies, animal studies, and traditional Chinese medicine interventions. The review highlights the potential of metabolomics in the diagnosis and treatment of IBS, as well as the role of traditional Chinese medicine in improving IBS.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Review
Nutrition & Dietetics
Ionela-Daniela Morariu, Liliana Avasilcai, Madalina Vieriu, Vasile Valeriu Lupu, Branco-Adrian Morariu, Ancuta Lupu, Paula-Cristina Morariu, Oana-Lelia Pop, Iuliana Magalena Starcea, Laura Trandafir
Summary: Irritable bowel syndrome is a common gastrointestinal disease that causes various symptoms such as bloating, abdominal pain, and diarrhea. A low-FODMAP diet has been shown to effectively reduce these symptoms and improve the quality of life for patients with irritable bowel syndrome.
Article
Medicine, General & Internal
Juan J. Sebastian Domingo
Summary: Irritable bowel syndrome is a common functional bowel disorder with significant impact on patients' daily lives and society's economy. It is characterized by abdominal pain, bloating, and altered bowel movements, and its etiology and pathophysiological mechanism are still unknown.
Article
Biochemistry & Molecular Biology
Sholpan Omarova, Karem Awad, Verena Moos, Christoph Puening, Greta Goelz, Jorg-Dieter Schulzke, Roland Buecker
Summary: This study observed patients with persistent PI-IBS symptoms after C. jejuni infection and found that the epithelial resistance of the colon epithelium was unaltered, but the permeability of HRP increased and some inflammation-related markers were elevated. Therefore, targeting these mechanisms caused by the infection may help reduce sequelae such as PI-IBS.
Article
Multidisciplinary Sciences
A. Das, E. O'Herlihy, F. Shanahan, P. W. O'Toole, I. B. Jeffery
Summary: Alterations in the gut mycobiome were found to be significantly different between patients with Irritable Bowel Syndrome (IBS) and control subjects, but not among clinical subtypes of IBS. The mycobiome changes were significantly associated with alterations in the bacteriome and metabolome, but did not show a link with dietary habits. Despite co-variation with bacterial components, the mycobiome presents limited therapeutic and diagnostic potential for IBS.
SCIENTIFIC REPORTS
(2021)
Review
Plant Sciences
Qiang Lu, Daopeng Tan, Jingbin Luo, Yonghao Ye, Manhua Zuo, Siyu Wang, Cailan Li
Summary: This study systematically reviews the recent advancements of natural products as potential drugs for treating irritable bowel syndrome. It demonstrates that natural products could be promising candidate drugs for IBS therapy.
Review
Immunology
Lin Xiao, Qin Liu, Mei Luo, Lishou Xiong
Summary: Research has identified the significant roles that microbiota-derived metabolites play in the development of IBS symptoms in patients, shedding light on the complex interplay between gut microbiota and IBS.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Gastroenterology & Hepatology
Caterina Strisciuglio, Massimo Martinelli, Peter Lu, Michal Rozenfeld Bar Lev, Beate Beinvogl, Marc A. Benninga, Carlo Di Lorenzo, Francesca Fiori Nastro, Samuel Nurko, Haley Pearlstein, Rachel Rosen, Raanan Shamir, Annamaria Staiano
Summary: During the first phase of the COVID-19 pandemic, children with FAPDs experienced improved symptoms, with a decrease in abdominal pain episodes over time, and showed increased quality of life and anxiety levels.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2021)
Review
Gastroenterology & Hepatology
Giovanni Di Nardo, Cesare Cremon, Annamaria Staiano, Vincenzo Stanghellini, Osvaldo Borrelli, Caterina Strisciuglio, Claudio Romano, Saverio Mallardo, Elena Scarpato, Giovanni Marasco, Silvia Salvatore, Letizia Zenzeri, Enrico Felici, Licia Pensabene, Simona Sestito, Ruggiero Francavilla, Paolo Quitadamo, Mariella Baldassarre, Valentina Giorgio, Renato Tambucci, Chiara Ziparo, Pasquale Parisi, Maria Raffaella Barbaro, Giovanni Barbara
Summary: Functional gastrointestinal disorders, such as IBS, affect many children worldwide due to disturbed neuroimmune function. Low-grade inflammation and mucosal immune activation play a significant role in symptom generation among pediatric patients with IBS, potentially influencing new therapeutic strategies.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Pediatrics
Antonietta Giannattasio, Marco Maglione, Carolina D'Anna, Stefania Muzzica, Serena Pappacoda, Selvaggia Lenta, Onorina Di Mita, Giusy Ranucci, Claudia Mandato, Vincenzo Tipo
Summary: Liver and pancreatic involvement is commonly observed in children with MIS-C, but it is usually mild and results in complete recovery.
Letter
Clinical Neurology
Marco Maglione, Stefania Graziano, Carmela Russo, Antonietta Giannattasio, Vincenzo Tipo
CHILDS NERVOUS SYSTEM
(2022)
Letter
Pediatrics
Antonietta Giannattasio, Marco Maglione, Crescenzo Coppola, Francesca Di Candia, Marianna De Marco, Sonia Tamasi, Vincenzo Tipo
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
(2022)
Article
Biochemistry & Molecular Biology
Monica Gelzo, Antonietta Giannattasio, Marco Maglione, Stefania Muzzica, Carolina D'Anna, Filippo Scialo, Thaililja Gagliardo, Michela Grieco, Vincenzo Tipo, Giuseppe Castaldo
Summary: Endothelial hyperinflammation and vasculitis are common features in acute COVID-19 and MIS-C. The study found that MIS-C patients had higher levels of MCP-1 and VEGF-A at admission, followed by an increase in pANCA after one week. These findings suggest a potential involvement of vasculitis in the development of MIS-C.
Review
Chemistry, Multidisciplinary
Marco Maglione, Antonietta Giannattasio, Antonia Pascarella, Vincenzo Tipo
Summary: Montelukast is not a revolutionary drug for pediatric asthma management, but rather a second-line medication used when inhaled steroids are ineffective. However, concerns about its safety have arisen due to increasing side effects. This review summarizes the literature published since 2010 on the role of Montelukast in pediatric asthma, highlighting the controversial results and unanswered questions regarding its use.
APPLIED SCIENCES-BASEL
(2023)
Review
Pediatrics
Claudia Mandato, Angelo Colucci, Roberta Lanzillo, Annamaria Staiano, Elena Scarpato, Luigi Schiavo, Francesca Felicia Operto, Maria Rosaria Serra, Cristina Di Monaco, Julia Sara Napoli, Grazia Massa, Pietro Vajro
Summary: Purpose of this study was to explore the role of lifestyle and diet in the development and progression of multiple sclerosis (MS) and investigate the potential benefits of diets and dietary supplementations in improving patient outcomes. Findings revealed that there is no universally best diet for MS, but healthy and balanced diets rich in fruits, vegetables, whole grains, and lean proteins while limiting processed foods, sugar, and saturated fat appear to have antioxidant and anti-inflammatory properties and promote a gut microbiota that supports gut and brain barriers. Vitamin D and polyunsaturated fatty acids are the most studied supplements for reducing MS-associated inflammation. In addition, counseling on appropriate diet and maintaining physical activity is recommended for MS prevention and management in both adults and children until more research is available on newer approaches.
Article
Gastroenterology & Hepatology
Massimo Martinelli, Erminia Romeo, Tamara Caldaro, Konstantina Dimakou, Alexandra Papadopoulou, Manar Matar, Amit Assa, Valeria Dipasquale, Claudio Romano, Marina Aloi, Patrizia Alvisi, Dennis Roser, Kaija Leena Kolho, Nadeem Afzal, Oren Ledder, Schlomi Cohen, Jiri Bronsky, Johanna C. Escher, Annecarin Brueckner, Raanan Shamir, Annamaria Staiano, Erasmo Miele
Summary: This study aimed to determine the prevalence and predictive factors of Crohn's disease (CD) in children with ulcerative colitis (UC) after ileal pouch-anal anastomosis (IPAA). The results showed that children with UC undergoing IPAA had a high risk of developing subsequent CD, and a decreased preoperative body mass index was identified as a possible predictive factor for new-onset CD.
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Pediatrics
Elena Bozzola, Anna Maria Staiano, Giulia Spina, Nicola Zamperini, Francesco Marino, Marco Roversi, Giovanni Corsello
Summary: This study recruited a group of paediatric influencers to communicate information about children and adolescents' health on social media, showing a significant increase in engagement and reach. Most influencers reported positive experiences, demonstrating the potential success of using influencers to promote correct communication about children's and adolescents' health.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Article
Pediatrics
Alessandro Rossi, Erasmo Miele, Simona Fecarotta, Maria Veiga-da-Cunha, Massimo Martinelli, Carmine Mollica, Maria D'Armiento, Enza Mozzillo, Pietro Strisciuglio, Terry G. J. Derks, Annamaria Staiano, Giancarlo Parenti
Summary: This study presents for the first time extensive gastrointestinal morphology follow-up in a GSD Ib patient receiving empagliflozin. The results suggest that this treatment can safely and effectively induce IBD remission, potentially postponing surgery. Future studies are needed to confirm long-term effects and assess benefits in different disease stages.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Article
Pediatrics
Massimo Martinelli, Lucia Quaglietta, Giuseppe Banderali, Pietro Ferrara, Claudio Romano, Annamaria Staiano
Summary: The study found that Italian pediatricians have a sufficient awareness of ibuprofen-prescribing patterns, but there is a concern regarding the relatively high percentage of pediatricians who combine/alternate the use of ibuprofen and paracetamol. The reported adverse events were mostly mild and often related to errors in dosage, frequency, and treatment duration, emphasizing the need for caution in both practitioners and patients in their use.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Article
Pediatrics
Paolo Quitadamo, Nikhil Thapar, Giovanni Di Nardo, Matilde Pescarin, Luca Bertelli, Clelia Tortora, Osvaldo Borrelli, Roberto De Giorgio, Annamaria Staiano
Summary: The study found a higher prevalence of joint hypermobility (JH) in children with ulcerative colitis, but the difference compared to the healthy controls did not reach statistical significance. Further investigation is needed to determine if JH can be considered a potential feature of pediatric GI disorders.
TURKISH JOURNAL OF PEDIATRICS
(2021)
Letter
Pediatrics
Riccardo Davanzo, Massimo Agosti, Irene Cetin, Antonio Chiantera, Giovanni Corsello, Luca A. Ramenghi, Annamaria Staiano, Marcello Tavio, Alberto Villani, Elsa Viora, Fabio Mosca
Summary: Although knowledge about the administration of COVID-19 vaccine to breastfeeding mothers is limited, Italian scientific societies concluded that COVID-19 vaccination is compatible with breastfeeding due to the well-demonstrated health benefits of breastfeeding and the unlikely health risks for nursed infants according to biological plausibility.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Review
Pediatrics
Lucia Quaglietta, Massimo Martinelli, Annamaria Staiano
Summary: Ibuprofen in children may lead to severe adverse events, including necrotizing soft tissue infections during chickenpox, which suggests cautious use.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Article
Pediatrics
Tarun Aurora, Audrey Cole, Parul Rai, Paul Lavoie, Carrie Mcivor, Lisa M. Klesges, Guolian Kang, Janaka S. S. Liyanage, Heather M. Brandt, Jane S. Hankins
Summary: This study evaluated the effectiveness of a vaccine strategy bundle in increasing HPV vaccine initiation and completion rates in a specialty clinic setting. By implementing the bundle, which included staff education, provider incentives, offering vaccines in clinics, and verifying vaccine completion, the clinic successfully improved HPV vaccine initiation and completion rates among sickle cell disease patients.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nienke M. Halbmeijer, Wes Onland, Jeroen Dudink, Filip Cools, Anne Debeer, Anton H. van Kaam, Manon J. N. L. Benders, Niek E. van der Aa
Summary: In ventilated infants born preterm, high dose systemic hydrocortisone initiated between 7 and 14 days after birth did not have a significant impact on brain development.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Katherine Melton, Jianfang Liu, Hossein Sadeghi, Maureen George, Arlene Smaldone
Summary: This study aims to identify predictors of change in lung function and body weight during health care transition in cystic fibrosis (CF) patients. The study findings highlight the importance of CF RISE program engagement and reducing gaps in care for improving the transition of adolescents and young adults with CF.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Laura A. Duckworth, Kimberly A. Sutton, Nurmohammad Shaikh, Jinli Wang, Carla Hall-Moore, Lori R. Holtz, Phillip I. Tarr, Ronald C. Rubenstein
Summary: The study tested the usefulness of various biomarkers as indicators of gut dysfunction in cystic fibrosis (CF) and investigated the repeatability of these measures in individuals over short periods and their correlation with clinical outcomes. The results showed that elevated levels of fLcn2 in individuals with CF may predict worsened pulmonary function.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Lindsey Haack, Nikkan Das, Arvind Hoskoppal, Mark Debrunner, Tarek Alsaied, Gaurav Arora
Summary: RAE on ECG has a low positive predictive value for RAE on echocardiogram in previously healthy young patients. The highest yield for RAE on echocardiogram was observed in patients who were <1 year of age, had RAE in the anterior precordial leads, or displayed right ventricular hypertrophy on ECG.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael A. Padula, Khatija Naing, Tara L. Wenger, Irfan Ahmad, Carl H. Coghill, K. Taylor Wild, S. Alex Rottgers, Cory M. Resnick, Jeffrey Goldstein, Zarmina Ehsan, Donna Watkins, Nicole Deptula, Kuan-Chi Lai, Janet Lioy, Semsa Gogcu, Christopher M. Cielo
Summary: This study describes the spectrum of disease and burden of care in infants with congenital micrognathia. The results show that these infants commonly require surgical intervention and tube feedings, and disparities based on race and among centers were identified.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael P. Fundora, Manvitha Kalicheti, Guantao Zhao, Kevin O. Maher, Nicoleta Serban
Summary: This study investigated the variation of outpatient opioid prescribing in postoperative pediatric cardiac patients across the US. The results showed that there were significant differences in opioid prescribing by race, ethnicity, sex, and region.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Jia Guo, Brooklyn J. Fraser, Leigh Blizzard, Michael D. Schmidt, Terence Dwyer, Alison J. Venn, Costan G. Magnussen
Summary: There is a correlation between childhood and adulthood cardiorespiratory fitness.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G. Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki, Keia Sanderson, Ikuyo Yamaguchi, Stephen D. Cha, Michael G. Semanik, Rahul Chanchlani, Joseph T. Flynn, Mark Mitsnefes
Summary: This multicenter study reports that most infants diagnosed with idiopathic hypertension in the NICU will discontinue antihypertensive treatment within 2 years of discharge. Antenatal steroid treatment is associated with a decreased likelihood of needing antihypertensive therapy for more than 1 year.
JOURNAL OF PEDIATRICS
(2024)
Editorial Material
Pediatrics
Kanwaljit Singh, John Concato, Jonathan M. Davis
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Yaxing Meng, Harri Niinikoski, Suvi P. Rovio, Brooklyn J. Fraser, Feitong Wu, Antti Jula, Tapani Ronnemaa, Jorma S. A. Viikari, Olli T. Raitakari, Katja Pahkala, Costan G. Magnussen
Summary: This 26-year study shows a correlation between early-life non-HDL-C levels and future levels. Early dietary counseling can reduce the risk of high pediatric non-HDL-C, emphasizing the importance of early interventions in preventing cardiovascular risks.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kelsey A. B. Gastineau, Rebecca Bell, Allison Hanes, Sandra Mckay, Eric Sigel, Filoteia Popescu, Evan C. Sommer, Shari Barkin
Summary: This study aimed to assess the self-reported counseling outcomes for a firearm safe storage counseling training program provided by the American Academy of Pediatrics. The results demonstrated significant improvement in counseling self-efficacy and frequency one month after the training.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kathryn E. K. Berlin, William Scott, Sara Dawson, David Brousseau, Joanne M. Lagatta
Summary: This prospective cohort study aimed to investigate the impact of bronchopulmonary dysplasia (BPD) on the health-related quality of life (HRQL) of infants from NICU hospitalization to one year post-discharge. The study found that lower HRQL during NICU stay was associated with earlier gestational age, postnatal corticosteroid usage, outborn status, and gastrostomy tube placement. Lower HRQL at 3 and 12 months post-discharge was associated with readmissions, home oxygen use, parent-reported difficulty breathing, lower developmental scores, and not playing with other children. Most parents reported similar or improved HRQL after discharge, but parents of infants with respiratory symptoms experienced less improvement. Efforts to improve parent HRQL should focus on respiratory symptoms and social isolation.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Garett J. Griffith, Alan P. Wang, Robert I. Liem, Michael R. Carr, Tyler Corson, Kendra Ward
Summary: This study developed reference values for cardiorespiratory fitness in children aged 6-18 years without underlying heart disease, measured by peak oxygen uptake and treadmill time. Fitness levels increased with age in males but not females. Males generally exhibited higher fitness levels compared to females in the same age groups.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
David S. Liu, Patricia Miller, Anna Rothenberg, Carley Vuillermin, Peter M. Waters, Andrea S. Bauer
Summary: This study aims to determine if children with elbow flexion contracture (EFC) caused by brachial plexus birth injury (BPBI) are more likely to develop shoulder contracture and undergo surgical treatment. A retrospective review was conducted on children under 2 years old with BPBI who presented to a single children's hospital. The results showed that patients with EFC had reduced shoulder range of motion and higher odds of shoulder contracture and surgical treatment. Prompt referral to a BPBI specialty clinic is recommended for evaluation and potential surgery.
JOURNAL OF PEDIATRICS
(2024)
