4.3 Article

Systematic Evaluation of Diagnostic Delay in Pediatric Inflammatory Bowel Disease

Journal

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MPG.0000000000001238

Keywords

Crohn disease; diagnostic delay; pediatric inflammatory bowel diseases; ulcerative colitis

Funding

  1. Swiss National Science Foundation [33CS30_148422, 32003B_160115/1, 310030-120312, 320000-114009/3, 32473B_135694/1]
  2. Otsuka Switzerland
  3. Takeda Switzerland
  4. Tillotts Switzerland

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We evaluated the diagnostic delay (time from first symptoms to diagnosis) in 100 pediatric patients with Crohn disease (CD) and 75 patients with ulcerative colitis (UC). Median (interquartile range) diagnostic delay in patients with CD was 4 (2-8) (range 0-82) months compared with 2 (1-7) (range 0-52) months in patients with UC (P = 0.003). The time interval from first physician visit to inflammatory bowel disease diagnosis was longer in patients with CD and UC when compared to the time interval from symptom onset to first physician visit (CD: median 3 vs 1 months, P < 0.001; UC: median 2 vs 0 months, P < 0.001). No specific risk factors were identified for the length of diagnostic delay. Measures should be taken to reduce diagnostic delay.

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