Bacterial subversion of cAMP signalling inhibits cathelicidin expression, which is required for innate resistance to Mycobacterium tuberculosis

A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis

(2015) Bappaditya Dey et al.   NATURE MEDICINE

Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics

(2014) Anca Dorhoi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Acceleration of Tuberculosis Treatment by Adjunctive Therapy with Verapamil as an Efflux Inhibitor

(2013) Shashank Gupta et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dynamic Roles of Type I and Type II IFNs in Early Infection with Mycobacterium tuberculosis

(2012) L. Desvignes et al.   JOURNAL OF IMMUNOLOGY

Cathelicidin is involved in the intracellular killing of mycobacteria in macrophages

(2011) Avinash Sonawane et al.   CELLULAR MICROBIOLOGY

Mammalian antimicrobial peptide influences control of cutaneous Leishmania infection

(2011) Manjusha M. Kulkarni et al.   CELLULAR MICROBIOLOGY

Cathelicidin Antimicrobial Peptide LL-37 in Psoriasis Enables Keratinocyte Reactivity against TLR9 Ligands

(2011) Shin Morizane et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Peptide gomesin triggers cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species

(2010) Rossana C. Soletti et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The human cathelicidin, LL-37, induces granzyme-mediated apoptosis in cytotoxic T lymphocytes

(2010) Jamie S. Mader et al.   EXPERIMENTAL CELL RESEARCH

LL-37 Directs Macrophage Differentiation toward Macrophages with a Proinflammatory Signature

(2010) A. M. van der Does et al.   JOURNAL OF IMMUNOLOGY

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils

(2009) Zhifang Zhang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

cAMP Stringently Regulates Human Cathelicidin Antimicrobial Peptide Expression in the Mucosal Epithelial Cells by Activating cAMP-response Element-binding Protein, AP-1, and Inducible cAMP Early Repressor

(2009) Krishnendu Chakraborty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase

(2009) Nisheeth Agarwal et al.   NATURE

Voltage Gated Calcium Channels Negatively Regulate Protective Immunity to Mycobacterium tuberculosis

(2009) Shashank Gupta et al.   PLoS One

Bacterial exotoxins downregulate cathelicidin (hCAP-18/LL-37) and human β-defensin 1 (HBD-1) expression in the intestinal epithelial cells

(2008) Krishnendu Chakraborty et al.   CELLULAR MICROBIOLOGY