Intra-articular dexamethasone to inhibit the development of post-traumatic osteoarthritis

Charge based intra-cartilage delivery of single dose dexamethasone using Avidin nano-carriers suppresses cytokine-induced catabolism long term

(2016) A.G. Bajpayee et al.   OSTEOARTHRITIS AND CARTILAGE

Dexamethasone enhances programmed cell death 1 (PD-1) expression during T cell activation: an insight into the optimum application of glucocorticoids in anti-cancer therapy

(2015) Kailin Xing et al.   BMC IMMUNOLOGY

Assessment of cortical and trabecular bone changes in two models of post-traumatic osteoarthritis

(2015) Hannah M. Pauly et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Single intra-articular dexamethasone injection immediately post-surgery in a rabbit model mitigates early inflammatory responses and post-traumatic osteoarthritis-like alterations

(2015) Bryan J. Heard et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of insulin-like growth factor-1 and dexamethasone on cytokine-challenged cartilage: relevance to post-traumatic osteoarthritis

(2015) Y. Li et al.   OSTEOARTHRITIS AND CARTILAGE

DAMPs from Cell Death to New Life

(2015) Emilie Vénéreau et al.   Frontiers in Immunology

Pathogenesis of post-traumatic OA with a view to intervention

(2014) Edward A. Riordan et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Progress in intra-articular therapy

(2013) Christopher H. Evans et al.   Nature Reviews Rheumatology

Cartilage and bone markers and inflammatory cytokines are increased in synovial fluid in the acute phase of knee injury (hemarthrosis) – a cross-sectional analysis

(2012) P. Swärd et al.   OSTEOARTHRITIS AND CARTILAGE

Local administration of glucocorticoids decreases synovial citrullination in rheumatoid arthritis

(2012) Dimitrios Makrygiannakis et al.   ARTHRITIS RESEARCH & THERAPY

Dexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia

(2011) Yingqian Huo et al.   BMC NEUROSCIENCE

Potentiation of pro-inflammatory cytokine suppression and survival by microencapsulated dexamethasone in the treatment of experimental sepsis

(2011) Mohammad N. Uddin et al.   JOURNAL OF DRUG TARGETING

Post-traumatic osteoarthritis: Improved understanding and opportunities for early intervention

(2011) Donald D. Anderson et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines

(2011) Yihong CS Lu et al.   ARTHRITIS RESEARCH & THERAPY

Cytokine Profiling in Acute Anterior Cruciate Ligament Injury

(2010) Vanessa G. Cuellar et al.   ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY

Glucocorticoids reduce nitric oxide concentration in middle ear effusion from lipopolysaccharide induced otitis media

(2010) Charles Pudrith et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Identification and Clonal Characterisation of a Progenitor Cell Sub-Population in Normal Human Articular Cartilage

(2010) Rebecca Williams et al.   PLoS One

Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor α in immature bovine and adult human articular cartilage

(2009) Yihong Sui et al.   ARTHRITIS AND RHEUMATISM

Regulation of prostaglandin E2 synthesis in cells derived from chondrocytes of patients with osteoarthritis

(2009) Hisashi Shimpo et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Mechanical Injury and Cytokines Cause Loss of Cartilage Integrity and Upregulate Proteins Associated with Catabolism, Immunity, Inflammation, and Repair

(2009) Anna L. Stevens et al.   MOLECULAR & CELLULAR PROTEOMICS

IGF-1 does not moderate the time-dependent transcriptional patterns of key homeostatic genes induced by sustained compression of bovine cartilage

(2009) C.A. Wheeler et al.   OSTEOARTHRITIS AND CARTILAGE

Potent inhibition of cartilage biosynthesis by coincubation with joint capsule through an IL-1-independent pathway

(2009) P. Patwari et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS