4.7 Article

Flow Synthesis of Diaryliodonium Triflates

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 82, Issue 22, Pages 11735-11741

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b01346

Keywords

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Funding

  1. Dutch Science Foundation (NWO) by an ECHO grant [713.013.001]
  2. VIDI grant [14150]

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A safe and scalable synthesis of diaryliodonium triflates was achieved using a practical continuous-flow design. A wide array of electron-rich to electron-deficient arenes could readily be transformed to their respective diaryliodonium salts on a gram scale, with residence times varying from. 2 to 60 s (44 examples).

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