4.7 Article

Organoselenium-Catalyzed Oxidative C=C Bond Cleavage: A Relatively Green Oxidation of Alkenes into Carbonyl Compounds with Hydrogen Peroxide

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 82, Issue 18, Pages 9342-9349

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b01245

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Funding

  1. NNSFC [21202141]
  2. Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions
  3. Open Project Program of Jiangsu Key Laboratory of Zoonosis [R1509]
  4. High Level Talent Support Project of Yangzhou University

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A relatively green oxidative C=C bond cleavage of alkenes was achieved by organoselenium-catalyzed alkene oxidation reaction in ethanol with hydrogen peroxide, affording carbonyl compounds under relatively mild conditions. It is a new reaction style for the organoselenium-catalyzed oxidation of alkenes and largely contributes to the growing field of organoselenium catalysis.

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