4.7 Article

Palladium-Catalyzed Sequential Vinylic C-H Arylation/Amination of 2-Vinylanilines with Aryl boronic Acids: Access to 2-Arylindoles

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 83, Issue 1, Pages 323-329

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b02728

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Funding

  1. National Science Foundation of China [21302152]
  2. Key Science and Technology Innovation Team of shaanxi Province [2017KCT-37]
  3. Northwest University

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A palladium-catalyzed selective and successive vinylic C-H arylation/amination of 2-vinylanilines with arylboronic acids to generate indoles has been developed. This procedure represents a straightforward and practical approach to valuable multifudctionalized indoles.

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