Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 82, Issue 18, Pages 9410-9417Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b01405
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Funding
- NSFC [21472072, 21302077, 21290183]
- Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT) [IRT_15R28]
- FRFCU [lzujbky-2016-ct02, lzujbky-2014-188]
- 111 Program of MOE
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A chemoselective N-arylation reaction of 2-aminopyridine derivatives with arynes in good to excellent yields has been described. The N-arylation products could be further applied to the facile construction of benzoisoquinuclidines and isoquinuclidines as well as pyrido[1,2-a]-benzimidazoles.
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