Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-κB target gene expression in human microglia

MicroRNA-181c negatively regulates the inflammatory response in oxygen-glucose-deprived microglia by targeting Toll-like receptor 4

(2015) Li Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

(2015) J. Claude Hemphill et al.   STROKE

Brain region-specific gene expression profiles in freshly isolated rat microglia

(2015) Karlijn J. Doorn et al.   Frontiers in Cellular Neuroscience

Effects of thrombin on the secondary cerebral injury of perihematomal tissues of rats after intracerebral hemorrhage

(2014) C.M. Liu et al.   GENETICS AND MOLECULAR RESEARCH

Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microgliain vitro

(2014) Sandra D. Mulder et al.   GLIA

Early detection of thrombin activity in neuroinflammatory disease

(2013) Dimitrios Davalos et al.   ANNALS OF NEUROLOGY

Epigenetic Roles of MLL Oncoproteins Are Dependent on NF-κB

(2013) Hsu-Ping Kuo et al.   CANCER CELL

NF-κB: A Coordinator for Epigenetic Regulation by MLL

(2013) Susumu Goyama et al.   CANCER CELL

Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes

(2013) Emmette R. Hutchison et al.   GLIA

ROCK mediates the inflammatory response in thrombin induced microglia

(2013) Guiyun Cui et al.   NEUROSCIENCE LETTERS

TNF-alpha receptor antagonist, R-7050, improves neurological outcomes following intracerebral hemorrhage in mice

(2013) Melanie D. King et al.   NEUROSCIENCE LETTERS

Poststroke Outcomes Vary by Pathogenic Stroke Subtype in The Atherosclerosis Risk in Communities Study

(2013) S. B. Jones et al.   STROKE

Phenotyping primary human microglia: Tight regulation of LPS responsiveness

(2012) Jeroen Melief et al.   GLIA

MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB

(2012) Xiang Wang et al.   JOURNAL OF CELL SCIENCE

Regulated microRNAs in the CSF of patients with multiple sclerosis: A case-control study

(2012) A. Haghikia et al.   NEUROLOGY

Thrombin and hemin as central factors in the mechanisms of intracerebral hemorrhage–induced secondary brain injury and as potential targets for intervention

(2012) Ranjith Babu et al.   Neurosurgical Focus

Target Gene Repression Mediated by miRNAs miR-181c and miR-9 Both of Which Are Down-regulated by Amyloid-β

(2011) Nicole Schonrock et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

MicroRNAs in CNS injury: Potential roles and therapeutic implications

(2010) Sindhu K. Madathil et al.   BIOESSAYS

Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle

(2009) Bibhu P. Mishra et al.   FEBS Journal

Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II

(2009) P. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-κB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes

(2009) I Robert et al.   ONCOGENE

MicroRNA Expression in the Blood and Brain of Rats Subjected to Transient Focal Ischemia by Middle Cerebral Artery Occlusion

(2008) Kandiah Jeyaseelan et al.   STROKE