Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation

IL-15 up-regulates the MMP-9 expression levels and induces inflammatory infiltration of macrophages in polymyositis through regulating the NF-kB pathway

(2016) Wang Yan et al.   GENE

MMP-9 in translation: from molecule to brain physiology, pathology, and therapy

(2016) Behnam Vafadari et al.   JOURNAL OF NEUROCHEMISTRY

TLR2 and TLR9 modulate enteric nervous system inflammatory responses to lipopolysaccharide

(2016) Joan F. Burgueño et al.   Journal of Neuroinflammation

Matrix metalloproteinases as therapeutic targets for stroke

(2015) Yi Yang et al.   BRAIN RESEARCH

Inflammatory mediator release from primary rhesus microglia in response to Borrelia burgdorferi results from the activation of several receptors and pathways

(2015) Geetha Parthasarathy et al.   Journal of Neuroinflammation

Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders

(2015) Stefano G. Daniele et al.   Science Signaling

Activity dependent CAM cleavage and neurotransmission

(2015) Katherine Conant et al.   Frontiers in Cellular Neuroscience

Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders

(2015) Stefano G. Daniele et al.   Science Signaling

Feasibility of investigating differential proteomic expression in depression: implications for biomarker development in mood disorders

(2015) M A Frye et al.   Translational Psychiatry

Brain Inflammation is a Common Feature of HIV-Infected Patients without HIV Encephalitis or Productive Brain Infection

(2014) Eleonora Tavazzi et al.   CURRENT HIV RESEARCH

Pattern recognition receptors and central nervous system repair

(2014) Kristina A. Kigerl et al.   EXPERIMENTAL NEUROLOGY

Extracellular matrix regulation of inflammation in the healthy and injured spinal cord

(2014) Andrew D. Gaudet et al.   EXPERIMENTAL NEUROLOGY

Genetic Removal of Matrix Metalloproteinase 9 Rescues the Symptoms of Fragile X Syndrome in a Mouse Model

(2014) H. Sidhu et al.   JOURNAL OF NEUROSCIENCE

Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations

(2014) Michael A. van der Kooij et al.   Nature Communications

DAMP-Mediated Activation of NLRP3-Inflammasome in Brain Sterile Inflammation: The Fine Line between Healing and Neurodegeneration

(2014) Anna Rubartelli   Frontiers in Immunology

Stimulation of Monocytes by Placental Microparticles Involves Toll-Like Receptors and Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells

(2014) Marianne Simone Joerger-Messerli et al.   Frontiers in Immunology

Toll-Like Receptors: Sensor Molecules for Detecting Damage to the Nervous System

(2013) Hyunkyoung Lee et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Postnatal Disruption of the Disintegrin/Metalloproteinase ADAM10 in Brain Causes Epileptic Seizures, Learning Deficits, Altered Spine Morphology, and Defective Synaptic Functions

(2013) J. Prox et al.   JOURNAL OF NEUROSCIENCE

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Soluble ICAM-5, a Product of Activity Dependent Proteolysis, Increases mEPSC Frequency and Dendritic Expression of GluA1

(2013) Irina Lonskaya et al.   PLoS One

Assessing Activation States in Microglia

(2012) Carol A. Colton et al.   CNS & Neurological Disorders-Drug Targets

Matrix Metalloproteinase Dependent Cleavage of Cell Adhesion Molecules in the Pathogenesis of CNS Dysfunction with HIV and Methamphetamine

(2012) Katherine Conant et al.   CURRENT HIV RESEARCH

MT5-MMP, ADAM-10, and N-Cadherin Act in Concert To Facilitate Synapse Reorganization after Traumatic Brain Injury

(2012) Kelly M. Warren et al.   JOURNAL OF NEUROTRAUMA

Synaptic circuit remodelling by matrix metalloproteinases in health and disease

(2012) George W. Huntley   NATURE REVIEWS NEUROSCIENCE

MMPs and Soluble ICAM-5 Increase Neuronal Excitability within In Vitro Networks of Hippocampal Neurons

(2012) Mark Niedringhaus et al.   PLoS One

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

(2012) Catherine Diane Savage et al.   Frontiers in Immunology

The Drosophila Toll Signaling Pathway

(2011) S. Valanne et al.   JOURNAL OF IMMUNOLOGY

Inflammatory Cortical Demyelination in Early Multiple Sclerosis

(2011) Claudia F. Lucchinetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis

(2010) Helen Williams et al.   CARDIOVASCULAR RESEARCH

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?

(2010) S. Rivera et al.   JOURNAL OF NEUROSCIENCE

Hippocampal CA1 atrophy and synaptic loss during experimental autoimmune encephalomyelitis, EAE

(2010) Marina O Ziehn et al.   LABORATORY INVESTIGATION

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Matrix Metalloproteinase Proteolysis of the Myelin Basic Protein Isoforms Is a Source of Immunogenic Peptides in Autoimmune Multiple Sclerosis

(2009) Sergey A. Shiryaev et al.   PLoS One

Nucleocytoplasmic protein shuttling: the direct route in synapse-to-nucleus signaling

(2009) Bryen A. Jordan et al.   TRENDS IN NEUROSCIENCES

Multiphasic roles for matrix metalloproteinases after stroke

(2008) A ROSELL et al.   CURRENT OPINION IN PHARMACOLOGY

ICAM-5—A novel two-facetted adhesion molecule in the mammalian brain

(2008) Carl G. Gahmberg et al.   IMMUNOLOGY LETTERS

Quantitative imaging assay for NF-κB nuclear translocation in primary human macrophages

(2007) Mahdad Noursadeghi et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cleavage of myelin associated glycoprotein by matrix metalloproteinases

(2007) Elizabeth Milward et al.   JOURNAL OF NEUROIMMUNOLOGY