Tumor necrosis factor receptor-associated factor 6 participates in early brain injury after subarachnoid hemorrhage in rats through inhibiting autophagy and promoting oxidative stress

The autophagy-lysosomal system in subarachnoid haemorrhage

(2016) Haijian Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A20 Ameliorates Intracerebral Hemorrhage–Induced Inflammatory Injury by Regulating TRAF6 Polyubiquitination

(2016) Zhaoyou Meng et al.   JOURNAL OF IMMUNOLOGY

S100B raises the alert in subarachnoid hemorrhage

(2016) Zhao Zhong Chong   REVIEWS IN THE NEUROSCIENCES

Recombinant Osteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/Integrin-Linked Kinase/Rac-1 Pathway After Subarachnoid Hemorrhage in Rats

(2016) Jiang Wu et al.   STROKE

Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy

(2015) Stefan Drießen et al.   Autophagy

Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats

(2015) Baoqi Dang et al.   CRITICAL CARE MEDICINE

TLR4-MyD88-TRAF6-TAK1 Complex-Mediated NF-κB Activation Contribute to the Anti-Inflammatory Effect of V8 in LPS-Induced Human Cervical Cancer SiHa Cells

(2015) Aiqin He et al.   INFLAMMATION

Role of Neurexin-1β and Neuroligin-1 in Cognitive Dysfunction After Subarachnoid Hemorrhage in Rats

(2015) Haitao Shen et al.   STROKE

Aneurysmal Subarachnoid Hemorrhage—Status Quo and Perspective

(2015) Nima Etminan   Translational Stroke Research

To be or not to be, the level of autophagy is the question: Dual roles of autophagy in the survival response to starvation

(2014) Chanhee Kang et al.   Autophagy

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

(2014) Ya-Dan Wen et al.   Autophagy

The rodent endovascular puncture model of subarachnoid hemorrhage: mechanisms of brain damage and therapeutic strategies

(2014) Elke Kooijman et al.   Journal of Neuroinflammation

TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling

(2014) Ying Lu et al.   PAIN

What is Early Brain Injury?

(2014) Hidenori Suzuki   Translational Stroke Research

Neuroprotective effect of bicyclol in rat ischemic stroke: Down-regulates TLR4, TLR9, TRAF6, NF-κB, MMP-9 and up-regulates claudin-5 expression

(2013) Jian Zhang et al.   BRAIN RESEARCH

The Involvement of Programmed Cell Death 5 (PDCD5) in the Regulation of Apoptosis in Cerebral Ischemia/Reperfusion Injury

(2013) Chun-Hua Chen et al.   CNS Neuroscience & Therapeutics

Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia

(2013) Linli Yao et al.   Journal of Neuroinflammation

Phosphatidylethanolamine binding protein 1 in vacular endothelial cell autophagy and atherosclerosis

(2013) Li Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells

(2013) Juan F. Linares et al.   MOLECULAR CELL

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6

(2013) Francesca Nazio et al.   NATURE CELL BIOLOGY

P2X7R/cryopyrin inflammasome axis inhibition reduces neuroinflammation after SAH

(2013) Sheng Chen et al.   NEUROBIOLOGY OF DISEASE

Controversies and evolving new mechanisms in subarachnoid hemorrhage

(2013) Sheng Chen et al.   PROGRESS IN NEUROBIOLOGY

Current Management of Delayed Cerebral Ischemia: Update from Results of Recent Clinical Trials

(2013) Shakira Brathwaite et al.   Translational Stroke Research

Immune-related GTPase M (IRGM1) regulates neuronal autophagy in a mouse model of stroke

(2012) Shuyu He et al.   Autophagy

TRAF6 inhibits proangiogenic signals in endothelial cells and regulates the expression of vascular endothelial growth factor

(2012) Sarah Bruneau et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuroprotective effect of early and short-time applying sophoridine in pMCAO rat brain: Down-regulated TRAF6 and up-regulated p-ERK1/2 expression, ameliorated brain infaction and edema

(2012) Zongjie Liu et al.   BRAIN RESEARCH BULLETIN

DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats

(2012) Shuang-Yong Sun et al.   BRAIN RESEARCH BULLETIN

Delayed cerebral ischaemia after subarachnoid haemorrhage: looking beyond vasospasm

(2012) M.J. Rowland et al.   BRITISH JOURNAL OF ANAESTHESIA

Signal transduction by tumor necrosis factor receptors

(2012) Lucía Cabal-Hierro et al.   CELLULAR SIGNALLING

Delayed Cerebral Ischemia after Subarachnoid Hemorrhage: From Vascular Spasm to Cortical Spreading Depolarizations

(2012) Zelong Zheng et al.   CURRENT NEUROVASCULAR RESEARCH

Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model

(2012) Zhong Wang et al.   JOURNAL OF PINEAL RESEARCH

Crucial Role of CD40 Signaling in Vascular Wall Cells in Neointimal Formation and Vascular Remodeling After Vascular Interventions

(2011) Zifang Song et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Associates with Huntingtin Protein and Promotes Its Atypical Ubiquitination to Enhance Aggregate Formation

(2011) Silvia Zucchelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Autophagy in Early Brain Injury after Experimental Subarachnoid Hemorrhage

(2011) Zhong Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage

(2011) Gang Chen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

CHOP Silencing Reduces Acute Brain Injury in the Rat Model of Subarachnoid Hemorrhage

(2011) Zhaohui He et al.   STROKE

Increased Expression of TNF Receptor-Associated Factor 6 After Rat Traumatic Brain Injury

(2010) Jian Chen et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains

(2010) Silvia Zucchelli et al.   HUMAN MOLECULAR GENETICS

Metamorphosis of Subarachnoid Hemorrhage Research: from Delayed Vasospasm to Early Brain Injury

(2010) Fatima A. Sehba et al.   MOLECULAR NEUROBIOLOGY

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Mechanisms of Osteopontin-Induced Stabilization of Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Rats

(2010) Hidenori Suzuki et al.   STROKE

Postischemic treatment of neonatal cerebral ischemia should target autophagy

(2009) Julien Puyal et al.   ANNALS OF NEUROLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Targeting autophagy to prevent neonatal stroke damage

(2009) Julien Puyal et al.   Autophagy

Angiotensin II Modulates BBB Permeability via Activation of the AT1 Receptor in Brain Endothelial Cells

(2009) Melissa A Fleegal-DeMotta et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Transcriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiency

(2009) Lola Rahib et al.   MOLECULAR GENETICS AND METABOLISM

The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

(2009) W.-L. Yang et al.   SCIENCE

Free Radical Injury and Blood-Brain Barrier Permeability in Hypoxic-Ischemic Encephalopathy

(2008) A. Kumar et al.   PEDIATRICS

Clazosentan to Overcome Neurological Ischemia and Infarction Occurring After Subarachnoid Hemorrhage (CONSCIOUS-1)

(2008) R. Loch Macdonald et al.   STROKE

Subarachnoid Hemorrhage: Is It Time for a New Direction?

(2008) J. Cahill et al.   STROKE

Melatonin decreases mortality following severe subarachnoid hemorrhage

(2007) Robert E. Ayer et al.   JOURNAL OF PINEAL RESEARCH