Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro studies
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro
studies
Authors
Keywords
-
Journal
JOURNAL OF NEUROCHEMISTRY
Volume 140, Issue 4, Pages 645-661
Publisher
Wiley
Online
2016-10-14
DOI
10.1111/jnc.13867
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Astrocyte roles in traumatic brain injury
- (2016) Joshua E. Burda et al. EXPERIMENTAL NEUROLOGY
- Repetitive head trauma, chronic traumatic encephalopathy and tau: Challenges in translating from mice to men
- (2016) Joseph O. Ojo et al. EXPERIMENTAL NEUROLOGY
- Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism
- (2016) A. R. Jayakumar et al. NEUROCHEMICAL RESEARCH
- The science and questions surrounding chronic traumatic encephalopathy
- (2016) Vin Shen Ban et al. Neurosurgical Focus
- Decreased astrocytic thrombospondin-1 secretion after chronic ammonia treatment reduces the level of synaptic proteins:in vitroandin vivostudies
- (2014) Arumugam R. Jayakumar et al. JOURNAL OF NEUROCHEMISTRY
- Activation of NF-κB Mediates Astrocyte Swelling and Brain Edema in Traumatic Brain Injury
- (2014) Arumugam R. Jayakumar et al. JOURNAL OF NEUROTRAUMA
- Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel
- (2014) Thor D Stein et al. Alzheimers Research & Therapy
- Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy
- (2013) Amy K. Clippinger et al. ACTA NEUROPATHOLOGICA
- Chronic cerebral ischemia induces redistribution and abnormal phosphorylation of transactivation-responsive DNA-binding protein-43 in mice
- (2013) Akihiro Shindo et al. BRAIN RESEARCH
- TDP-43 Phosphorylation by casein kinase Iε promotes oligomerization and enhances toxicity in vivo
- (2013) Darshana K. Choksi et al. HUMAN MOLECULAR GENETICS
- Blast-related traumatic brain injury
- (2013) Jeffrey V Rosenfeld et al. LANCET NEUROLOGY
- Chronic traumatic encephalopathy – neuropathology in athletes and war veterans
- (2013) Nelli Lakis et al. NEUROLOGICAL RESEARCH
- Clinical presentation of chronic traumatic encephalopathy
- (2013) R. A. Stern et al. NEUROLOGY
- Shrinkage of experimental benign prostatic hyperplasia and reduction of prostatic cell volume by a gastrin-releasing peptide antagonist
- (2013) F. G. Rick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The spectrum of disease in chronic traumatic encephalopathy
- (2012) Ann C. McKee et al. BRAIN
- Traumatic Brain Injury, Shell Shock, and Posttraumatic Stress Disorder in the Military—Past, Present, and Future
- (2012) Sharon B. Shively et al. JOURNAL OF HEAD TRAUMA REHABILITATION
- The JNK/c-Jun signaling axis contributes to the TDP-43-induced cell death
- (2012) Hiroaki Suzuki et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Metformin Inhibits Glutaminase Activity and Protects against Hepatic Encephalopathy
- (2012) Javier Ampuero et al. PLoS One
- Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans
- (2011) Victoria E. Johnson et al. ACTA NEUROPATHOLOGICA
- Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS
- (2011) Victòria Ayala et al. ACTA NEUROPATHOLOGICA
- Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury
- (2011) Arumugam R. Jayakumar et al. JOURNAL OF NEUROCHEMISTRY
- Astrocytes promote peripheral nerve injury-induced reactive synaptogenesis in the neonatal CNS
- (2011) Fu-Sun Lo et al. JOURNAL OF NEUROPHYSIOLOGY
- Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies
- (2011) Yohei Iguchi et al. NEUROBIOLOGY OF DISEASE
- Chronic traumatic encephalopathy in an Iraqi war veteran with posttraumatic stress disorder who committed suicide
- (2011) Bennet Omalu et al. Neurosurgical Focus
- Cytoplasmic Accumulation and Aggregation of TDP-43 upon Proteasome Inhibition in Cultured Neurons
- (2011) Janet van Eersel et al. PLoS One
- EF1alpha and RPL13a represent normalization genes suitable for RT-qPCR analysis of bone marrow derived mesenchymal stem cells
- (2010) Kevin M Curtis et al. BMC MOLECULAR BIOLOGY
- Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration
- (2010) Agnes L. Nishimura et al. BRAIN
- Progranulin deficiency leads to enhanced cell vulnerability and TDP-43 translocation in primary neuronal cultures
- (2010) Aobo Guo et al. BRAIN RESEARCH
- Nuclear factor TDP-43 can affect selected microRNA levels
- (2010) Emanuele Buratti et al. FEBS Journal
- Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes
- (2010) Chantelle F. Sephton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy
- (2010) Ann C. McKee et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis
- (2010) S. J. Barmada et al. JOURNAL OF NEUROSCIENCE
- Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy
- (2010) Tetsuaki Arai et al. NEUROPATHOLOGY
- A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome
- (2010) Octavio Garcia et al. PLoS One
- Identification of casein kinase-1 phosphorylation sites on TDP-43
- (2009) Fuyuki Kametani et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Metformin decreases angiogenesis via NF-κB and Erk1/2/Erk5 pathways by increasing the antiangiogenic thrombospondin-1
- (2009) Bee K. Tan et al. CARDIOVASCULAR RESEARCH
- Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis
- (2009) Çagla Eroglu et al. CELL
- TDP-43 is recruited to stress granules in conditions of oxidative insult
- (2009) Claudia Colombrita et al. JOURNAL OF NEUROCHEMISTRY
- Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury
- (2009) Ann C. McKee et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Axonal ligation induces transient redistribution of TDP-43 in brainstem motor neurons
- (2009) T. Sato et al. NEUROSCIENCE
- Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
- (2009) Y.-J. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells
- (2008) Takashi Nonaka et al. FEBS LETTERS
- Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS
- (2008) Yuki Inukai et al. FEBS LETTERS
- Na-K-Cl Cotransporter-1 in the Mechanism of Ammonia-induced Astrocyte Swelling
- (2008) Arumugam R. Jayakumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thrombospondins 1 and 2 are Necessary for Synaptic Plasticity and Functional Recovery after Stroke
- (2008) Jason Liauw et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Trauma-Induced Cell Swelling in Cultured Astrocytes
- (2008) Arumugam R. Jayakumar et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- TSP-1 Secreted by Bone Marrow Stromal Cells Contributes to Retinal Ganglion Cell Neurite Outgrowth and Survival
- (2008) Keming Yu et al. PLoS One
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started