Astrocytes contribute to Aβ-induced blood-brain barrier damage through activation of endothelial MMP9

The blood-brain barrier in Alzheimer's disease

(2017) Elena Zenaro et al.   NEUROBIOLOGY OF DISEASE

Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role

(2017) C. J. Garwood et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Vascular Endothelial Barrier Dysfunction Mediated by Amyloid-β Proteins

(2017) Enika Nagababu et al.   JOURNAL OF ALZHEIMERS DISEASE

Glial-endothelial crosstalk regulates blood–brain barrier function

(2016) Lara Cheslow et al.   CURRENT OPINION IN PHARMACOLOGY

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2016) Harm J. van de Haar et al.   RADIOLOGY

Mechanisms of Aβ Clearance and Degradation by Glial Cells

(2016) Miriam Ries et al.   Frontiers in Aging Neuroscience

Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition

(2016) Himakarnika Alluri et al.   PLoS One

Astrocytic TYMP and VEGFA drive blood–brain barrier opening in inflammatory central nervous system lesions

(2015) Candice Chapouly et al.   BRAIN

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Aβ1-42oligomer-induced leakage in anin vitroblood-brain barrier model is associated with up-regulation of RAGE and metalloproteinases, and down-regulation of tight junction scaffold proteins

(2015) Wenbin Wan et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation

(2015) Folami Lamoke et al.   Journal of Neuroinflammation

Amyloid   Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases

(2015) M. Brkic et al.   JOURNAL OF NEUROSCIENCE

Vascular dysfunction in the pathogenesis of Alzheimer's disease — A review of endothelium-mediated mechanisms and ensuing vicious circles

(2015) Luigi Yuri Di Marco et al.   NEUROBIOLOGY OF DISEASE

ETB receptor-mediated MMP-9 activation induces vasogenic edema via ZO-1 protein degradation following status epilepticus

(2015) J.Y. Kim et al.   NEUROSCIENCE

Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?

(2015) Simona F. Spampinato et al.   PLoS One

Astrocyte-derived retinoic acid: a novel regulator of blood–brain barrier function in multiple sclerosis

(2014) Mark R. Mizee et al.   ACTA NEUROPATHOLOGICA

Role of the Blood–Brain Barrier in Multiple Sclerosis

(2014) Genaro Gabriel Ortiz et al.   ARCHIVES OF MEDICAL RESEARCH

The neglected co-star in the dementia drama: the putative roles of astrocytes in the pathogeneses of major neurocognitive disorders

(2014) W K Jo et al.   MOLECULAR PSYCHIATRY

Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice

(2014) Sung Wook Park et al.   NEUROBIOLOGY OF AGING

The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes

(2014) Ilaria Dal Prà et al.   NEUROMOLECULAR MEDICINE

Aβ1–42 reduces P-glycoprotein in the blood–brain barrier through RAGE–NF-κB signaling

(2014) R Park et al.   Cell Death & Disease

Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer’s disease

(2014) Karina O. Garcia et al.   Frontiers in Aging Neuroscience

Autocrine MMP-2/9 secretion increases the BBB permeability in neuromyelitis optica

(2013) A. Tasaki et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

NMO sera down-regulate AQP4 in human astrocyte and induce cytotoxicity independent of complement

(2013) Hiroyo Haruki et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Effects of hyperbaric oxygen on MMP-2 and MMP-9 expression and spinal cord edema after spinal cord injury

(2013) Jing Yang et al.   LIFE SCIENCES

Pin1, endothelial nitric oxide synthase, and amyloid-β form a feedback signaling loop involved in the pathogenesis of Alzheimer’s disease, hypertension, and cerebral amyloid angiopathy

(2013) Jing-Zhang Wang et al.   MEDICAL HYPOTHESES

Neurovascular Dysfunction and Faulty Amyloid  -Peptide Clearance in Alzheimer Disease

(2013) A. P. Sagare et al.   Cold Spring Harbor Perspectives in Medicine

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

(2012) Azeb Tadesse Argaw et al.   JOURNAL OF CLINICAL INVESTIGATION

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling

(2012) S.-Y. Kook et al.   JOURNAL OF NEUROSCIENCE

Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation

(2012) Sara Merlo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

Targeting the neurovascular unit: Development of a new model and consideration for novel strategy for Alzheimer's disease

(2011) Rui Liu et al.   BRAIN RESEARCH BULLETIN

Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood-brain barrier function

(2010) Yasuteru Sano et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease

(2009) Robert D. Bell et al.   ACTA NEUROPATHOLOGICA

Cytokine regulation of tight junctions

(2008) Christopher T. Capaldo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Astrocytes in multiple sclerosis: A product of their environment

(2008) A. Nair et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tissue Inhibitor of Metalloproteinases Protect Blood—Brain Barrier Disruption in Focal Cerebral Ischemia

(2008) Motoaki Fujimoto et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Soluble aggregates of the amyloid-β protein selectively stimulate permeability in human brain microvascular endothelial monolayers

(2008) Francisco J. Gonzalez-Velasquez et al.   JOURNAL OF NEUROCHEMISTRY