Clk1-regulated aerobic glycolysis is involved in glioma chemoresistance

Knockdown of Cathepsin L promotes radiosensitivity of glioma stem cells both in vivo and in vitro

(2016) Wenjuan Wang et al.   CANCER LETTERS

Dihydropyrimidine Dehydrogenase Is a Prognostic Marker for Mesenchymal Stem Cell-Mediated Cytosine Deaminase Gene and 5-Fluorocytosine Prodrug Therapy for the Treatment of Recurrent Gliomas

(2016) Taemoon Chung et al.   Theranostics

Mitochondrial energy metabolism and apoptosis regulation in glioblastoma

(2015) Adam Nagy et al.   BRAIN RESEARCH

A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity

(2015) Richard M. Monaghan et al.   NATURE CELL BIOLOGY

Targeting Metabolic Remodeling in Glioblastoma Multiforme

(2015)   Oncotarget

Metabolic orchestration between cancer cells and tumor microenvironment as a co-evolutionary source of chemoresistance in ovarian cancer: A therapeutic implication

(2014) Dong Hoon Suh et al.   BIOCHEMICAL PHARMACOLOGY

Energy restriction mimetic agents to target cancer cells: Comparison between 2-deoxyglucose and thiazolidinediones

(2014) Sandra Kuntz et al.   BIOCHEMICAL PHARMACOLOGY

Identification of dual DNA-PK MDR1 inhibitors for the potentiation of cytotoxic drug activity

(2014) Emily Mould et al.   BIOCHEMICAL PHARMACOLOGY

HIF-1 Signaling in Drug Resistance to Chemotherapy

(2014) N.A. Warfel et al.   CURRENT MEDICINAL CHEMISTRY

Cordycepin Down-Regulates Multiple Drug Resistant (MDR)/HIF-1α through Regulating AMPK/mTORC1 Signaling in GBC-SD Gallbladder Cancer Cells

(2014) Wei-Ding Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The regulation of mitochondrial DNA copy number in glioblastoma cells

(2013) A Dickinson et al.   CELL DEATH AND DIFFERENTIATION

PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease

(2013) Cora O' Neill   EXPERIMENTAL GERONTOLOGY

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

Cellular immunotherapy for refractory hematological malignancies

(2013) John L Reagan et al.   Journal of Translational Medicine

Tumor glycolysis as a target for cancer therapy: progress and prospects

(2013) Shanmugasundaram Ganapathy-Kanniappan et al.   Molecular Cancer

Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

(2012) Y.-L. Hu et al.   CANCER RESEARCH

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Drug Resistance in Glioblastoma: A Mini Review

(2012) Catherine P. Haar et al.   NEUROCHEMICAL RESEARCH

Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning

(2011) Lara Milane et al.   Cancer Cell International

A Pairwise Chemical Genetic Screen Identifies New Inhibitors of Glucose Transport

(2011) Olesya A. Ulanovskaya et al.   CHEMISTRY & BIOLOGY

Mitochondrial Dysfunction Confers Resistance to Multiple Drugs in Caenorhabditis elegans

(2010) Iryna O. Zubovych et al.   MOLECULAR BIOLOGY OF THE CELL

Reversal of the Mitochondrial Phenotype and Slow Development of Oxidative Biomarkers of Aging in Long-livedMclk1+/−Mice

(2009) Jérôme Lapointe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated Mitochondrial Reactive Oxygen Species Generation Affects the Immune Response via Hypoxia-Inducible Factor-1  in Long-Lived Mclk1+/- Mouse Mutants

(2009) D. Wang et al.   JOURNAL OF IMMUNOLOGY

Down-regulation of lipocalin 2 contributes to chemoresistance in glioblastoma cells

(2009) Long Tai Zheng et al.   JOURNAL OF NEUROCHEMISTRY

Mechanisms of Chemoresistance to Alkylating Agents in Malignant Glioma

(2008) J. N. Sarkaria et al.   CLINICAL CANCER RESEARCH

Early Mitochondrial Dysfunction in Long-livedMclk1+/-Mice

(2008) Jérôme Lapointe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemoresistance in gliomas

(2008) Chen Lu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY