Protection against β-amyloid neurotoxicity by a non-toxic endogenous N-terminal β-amyloid fragment and its active hexapeptide core sequence

Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain

(2017) Michal Arbel-Ornath et al.   Molecular Neurodegeneration

Local and Use-Dependent Effects of β-Amyloid Oligomers on NMDA Receptor Function Revealed by Optical Quantal Analysis

(2016) Brooke L. Sinnen et al.   JOURNAL OF NEUROSCIENCE

(I) Pharmacological profiling of a novel modulator of the α7 nicotinic receptor: Blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer brains

(2016) Sara Garcia-Ratés et al.   NEUROPHARMACOLOGY

Activation of α7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons

(2015) Qing Cheng et al.   NEUROPHARMACOLOGY

GalaxyPepDock: a protein–peptide docking tool based on interaction similarity and energy optimization

(2015) Hasup Lee et al.   NUCLEIC ACIDS RESEARCH

Regulation of Presynaptic Ca2+, Synaptic Plasticity and Contextual Fear Conditioning by a N-terminal  -Amyloid Fragment

(2014) J. L. M. Lawrence et al.   JOURNAL OF NEUROSCIENCE

Impact of Sustained Exposure to β-Amyloid on Calcium Homeostasis and Neuronal Integrity in Model Nerve Cell System Expressing α4β2 Nicotinic Acetylcholine Receptors

(2013) Komal Arora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid beta peptide 1–42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures

(2011) I.L. Ferreira et al.   CELL CALCIUM

Role of Key Aromatic Residues in the Ligand-binding Domain of α7 Nicotinic Receptors in the Agonist Action of β-Amyloid

(2011) Mei Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist

(2011) Shu-Xing Li et al.   NATURE NEUROSCIENCE

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory

(2010) Daniela Puzzo et al.   ANNALS OF NEUROLOGY

β-Amyloid activates presynaptic α7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts

(2010) Ghous M. Khan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Hippocampal c-Jun-N-Terminal Kinases Serve as Negative Regulators of Associative Learning

(2010) T. Sherrin et al.   JOURNAL OF NEUROSCIENCE

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

HH Domain of Alzheimer’s Disease Aβ Provides Structural Basis for Neuronal Binding in PC12 and Mouse Cortical/Hippocampal Neurons

(2010) Joseph F. Poduslo et al.   PLoS One

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

(2010) M. M. Lipinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

A novel pathway for amyloid precursor protein processing

(2009) Erik Portelius et al.   NEUROBIOLOGY OF AGING

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice

(2008) Christina Priller et al.   NEUROBIOLOGY OF AGING

Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

(2008) Ryoichi Kimura et al.   NEUROBIOLOGY OF DISEASE

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

(2008) John R. Cirrito et al.   NEURON

Effects of chronic hypoxia on Ca2+ stores and capacitative Ca2+ entry in human neuroblastoma (SH-SY5Y) cells

(2003) I. F. Smith et al.   JOURNAL OF NEUROCHEMISTRY