SALL4 suppresses PTEN expression to promote glioma cell proliferation via PI3K/AKT signaling pathway

Knockdown of SALL4 Inhibits Proliferation, Migration, and Invasion in Osteosarcoma Cells

(2017) Dengfeng Zhang et al.   ONCOLOGY RESEARCH

Knockdown of SALL4 inhibits the proliferation and reverses the resistance of MCF-7/ADR cells to doxorubicin hydrochloride

(2016) Yuan-Yuan Chen et al.   BMC MOLECULAR BIOLOGY

SPOCK1 promotes the proliferation, migration and invasion of glioma cells through PI3K/AKT and Wnt/β-catenin signaling pathways

(2016) JINGHUI YANG et al.   ONCOLOGY REPORTS

Importance of SALL4 in the development and prognosis of hepatocellular carcinoma

(2016) Fei Yin et al.   WORLD JOURNAL OF GASTROENTEROLOGY

LIFR functions as a metastasis suppressor in hepatocellular carcinoma by negatively regulating phosphoinositide 3-kinase/AKT pathway

(2015) Qin Luo et al.   CARCINOGENESIS

LRIG1 inhibits hypoxia-induced vasculogenic mimicry formation via suppression of the EGFR/PI3K/AKT pathway and epithelial-to-mesenchymal transition in human glioma SHG-44 cells

(2015) Xi Zhang et al.   CELL STRESS & CHAPERONES

miR-494-3p Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by PTEN/AKT Signaling in Human Glioblastoma Cells

(2015) Xue-tao Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Cancer stem cells in oesophageal squamous cell carcinoma: Identification, prognostic and treatment perspectives

(2015) Farhadul Islam et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner

(2015) Samuel Milanovich et al.   EXPERIMENTAL HEMATOLOGY

Phosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth

(2015) Narendra Thapa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-κB Pathway

(2015) Ling-Li Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stemness factor Sall4 is required for DNA damage response in embryonic stem cells

(2015) Jianhua Xiong et al.   JOURNAL OF CELL BIOLOGY

Gab1 regulates SDF-1-induced progression via inhibition of apoptosis pathway induced by PI3K/AKT/Bcl-2/BAX pathway in human chondrosarcoma

(2015) Yongqian Fan et al.   TUMOR BIOLOGY

A comprehensive analysis of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) loss in colorectal cancer

(2015) Pei-Ching Lin et al.   World Journal of Surgical Oncology

SALL4 is a novel therapeutic target in intrahepatic cholangiocarcinoma

(2015) Gang Deng et al.   Oncotarget

SALL4 as an Epithelial-Mesenchymal Transition and Drug Resistance Inducer through the Regulation of c-Myc in Endometrial Cancer

(2015) Lei Liu et al.   PLoS One

The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-κB/cyclin D1 pathway in mouse mesangial cells

(2014) Xiao-Juan Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

SALL4 Expression in Germ Cell and Non–Germ Cell Tumors

(2014) Markku Miettinen et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Mechanisms involved in kinin-induced glioma cells proliferation: the role of ERK1/2 and PI3K/Akt pathways

(2014) Natália Fontana Nicoletti et al.   JOURNAL OF NEURO-ONCOLOGY

Sonic hedgehog–Gli1 signals promote epithelial–mesenchymal transition in ovarian cancer by mediating PI3K/AKT pathway

(2014) Zhang Ke et al.   MEDICAL ONCOLOGY

SALL4 positive fetal gut-like adenocarcinoma of the duodenum

(2014) Shoichi Kinoshita et al.   PATHOLOGY INTERNATIONAL

Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex

(2013) C. Gao et al.   BLOOD

Low-expression of microRNA-107 inhibits cell apoptosis in glioma by upregulation of SALL4

(2013) Jie He et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Enhancing bone marrow regeneration by SALL4 protein

(2013) Wenbin Liao et al.   Journal of Hematology & Oncology

Stem cell factor SALL4, a potential prognostic marker for myelodysplastic syndromes

(2013) Fei Wang et al.   Journal of Hematology & Oncology

The Role of EGFR/PI3K/Akt/cyclinD1 Signaling Pathway in Acquired Middle Ear Cholesteatoma

(2013) Wei Liu et al.   MEDIATORS OF INFLAMMATION

EGFR-mediated Akt and MAPKs signal pathways play a crucial role in patulin-induced cell proliferation in primary murine keratinocytes via modulation ofCyclin D1andCOX-2expression

(2013) Shamshad Alam et al.   MOLECULAR CARCINOGENESIS

Oncofetal Gene SALL4 in Aggressive Hepatocellular Carcinoma

(2013) Kol Jia Yong et al.   NEW ENGLAND JOURNAL OF MEDICINE

SALL4, a novel marker for human gastric carcinogenesis and metastasis

(2013) L Zhang et al.   ONCOGENE

SALL4 is a new target in endometrial cancer

(2013) A Li et al.   ONCOGENE

PTPN12 controls PTEN and the AKT signalling to FAK and HER2 in migrating ovarian cancer cells

(2012) Emma Villa-Moruzzi   MOLECULAR AND CELLULAR BIOCHEMISTRY

SALL4 is a key transcription regulator in normal human hematopoiesis

(2012) Chong Gao et al.   TRANSFUSION

The Phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 modulates cytokine expression in macrophages via p50 nuclear factor kappa B inhibition, in a PI3K-independent mechanism

(2011) Dorit Avni et al.   BIOCHEMICAL PHARMACOLOGY

NOTCH1 functions as an oncogene by regulating the PTEN/PI3K/AKT pathway in clear cell renal cell carcinoma

(2011) Shangwen Liu et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway

(2010) Venkata Ramesh Dasari et al.   PLoS One

Stem Cell Factor SALL4 Represses the Transcriptions of PTEN and SALL1 through an Epigenetic Repressor Complex

(2009) Jiayun Lu et al.   PLoS One