Topiramate via NMDA, AMPA/kainate, GABAA and Alpha2 receptors and by modulation of CREB/BDNF and Akt/GSK3 signaling pathway exerts neuroprotective effects against methylphenidate-induced neurotoxicity in rats

Neuroprotective effects of various doses of topiramate against methylphenidate induced oxidative stress and inflammation in rat isolated hippocampus

(2016) Majid Motaghinejad et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Involvement of AMPA/kainate and GABAA receptors in topiramate neuroprotective effects against methylphenidate abuse sequels involving oxidative stress and inflammation in rat isolated hippocampus

(2016) Majid Motaghinejad et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroprotective effects of various doses of topiramate against methylphenidate-induced oxidative stress and inflammation in isolated rat amygdala: the possible role of CREB/BDNF signaling pathway

(2016) Majid Motaghinejad et al.   JOURNAL OF NEURAL TRANSMISSION

Effects of acute doses of methylphenidate on inflammation and oxidative stress in isolated hippocampus and cerebral cortex of adult rats

(2016) Majid Motaghinejad et al.   JOURNAL OF NEURAL TRANSMISSION

Effects of chronic treatment with methylphenidate on oxidative stress and inflammation in hippocampus of adult rats

(2016) Majid Motaghinejad et al.   NEUROSCIENCE LETTERS

The neuroprotective effect of lithium against high dose methylphenidate: Possible role of BDNF

(2016) Majid Motaghinejad et al.   NEUROTOXICOLOGY

The effect of various morphine weaning regimens on the sequelae of opioid tolerance involving physical dependency, anxiety and hippocampus cell neurodegeneration in rats

(2015) Majid Motaghinejad et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

AMPK Plays a Dual Role in Regulation of CREB/BDNF Pathway in Mouse Primary Hippocampal Cells

(2015) Weidong Huang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Methylphenidate amplifies long-term potentiation in rat hippocampus CA1 area involving the insertion of AMPA receptors by activation of β-adrenergic and D1/D5 receptors

(2015) C. Rozas et al.   NEUROPHARMACOLOGY

Protective effects of various dosage of Curcumin against morphine induced apoptosis and oxidative stress in rat isolated hippocampus

(2015) Majid Motaghinejad et al.   Pharmacological Reports

Methylphenidate Exerts Dose-Dependent Effects on Glutamate Receptors and Behaviors

(2014) Jia Cheng et al.   BIOLOGICAL PSYCHIATRY

Brain apoptosis signaling pathways are regulated by methylphenidate treatment in young and adult rats

(2014) Gislaine Z. Réus et al.   BRAIN RESEARCH

Effects of Antiepileptic Drugs on Antioxidant and Oxidant Molecular Pathways: Focus on Trace Elements

(2013) Mustafa Nazıroğlu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

GDNF, NGF and BDNF as therapeutic options for neurodegeneration

(2013) Shelley J. Allen et al.   PHARMACOLOGY & THERAPEUTICS

GABA system changes in methylphenidate sensitized female rats

(2012) L. Freese et al.   BEHAVIOURAL BRAIN RESEARCH

Inflammation inhibits GABA transmission in multiple sclerosis

(2012) Silvia Rossi et al.   Multiple Sclerosis Journal

The mechanisms of antihyperalgesic effect of topiramate in a rat model of inflammatory hyperalgesia

(2011) Sonja Lj. Paranos et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Topiramate attenuates cerebral ischemia/reperfusion injury in gerbils via activating GABAergic signaling and inhibiting astrogliosis

(2011) Xiaoyuan Mao et al.   NEUROCHEMISTRY INTERNATIONAL

Alcohol Exposure Decreases CREB Binding Protein Expression and Histone Acetylation in the Developing Cerebellum

(2011) Weixiang Guo et al.   PLoS One

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

(2011) N. Soltani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of lamotrigine, oxcarbazepine and topiramate on cognitive functions and oxidative stress in PTZ-kindled mice

(2011) Nidhi Bharal Agarwal et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Alcohol-Induced Neurodegeneration, Suppression of Transforming Growth Factor-β, and Cognitive Impairment in Rats: Prevention by Group II Metabotropic Glutamate Receptor Activation

(2010) Andrea Cippitelli et al.   BIOLOGICAL PSYCHIATRY

Topiramate-antagonism of L-glutamate-induced paroxysms in planarians

(2010) Robert B. Raffa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Targeting CREB signalling in neurogenesis

(2010) Sebastian Dworkin et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Genetic association of the interaction between the BDNF and GSK3B genes and major depressive disorder in a Chinese population

(2009) Kerang Zhang et al.   JOURNAL OF NEURAL TRANSMISSION

Role of dopamine receptor mechanisms in the amygdaloid modulation of fear and anxiety: Structural and functional analysis

(2009) Miguel Pérez de la Mora et al.   PROGRESS IN NEUROBIOLOGY

IL-6 Levels in Migraine Patients Receiving Topiramate

(2009) Abdulkadir Koçer et al.   Pain Practice

Topiramate and Vitamin E Modulate Antioxidant Enzyme Activities, Nitric Oxide and Lipid Peroxidation Levels in Pentylenetetrazol-Induced Nephrotoxicity in Rats

(2008) Abdullah Armaǧan et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons

(2008) Pascal Steullet et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of Methylphenidate on the Catecholaminergic System in Attention-Deficit/Hyperactivity Disorder

(2008) Timothy E. Wilens   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Behavioural characterisation of rats exposed neonatally to bisphenol-A: responses to a novel environment and to methylphenidate challenge in a putative model of attention-deficit hyperactivity disorder

(2008) Motori Kiguchi et al.   JOURNAL OF NEURAL TRANSMISSION

Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis?

(2008) James M Kelley et al.   Journal of Neuroinflammation

Glutathione: a novel treatment target in psychiatry

(2008) Michael Berk et al.   TRENDS IN PHARMACOLOGICAL SCIENCES