Journal
JOURNAL OF NATURAL PRODUCTS
Volume 80, Issue 5, Pages 1674-1678Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.5b00828
Keywords
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Funding
- FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo, as part of Biota-FAPESP, the Biodiversity Virtual Institute Program) [03/02176-7, 2010/52327-5, 2013/07600-3]
- CNPq (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico)
- CAPES (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior)
- FAPESP [2011/03017-6]
- CAPES
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [13/07600-3, 11/03017-6] Funding Source: FAPESP
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Three new isoaigialones, A, B, and C (1-3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compounds 2 and 4 were active against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum. This is the first report of metabolites produced by an Phaeoacremonium sp., associated with S. spectabilis.
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