Journal
JOURNAL OF NATURAL PRODUCTS
Volume 80, Issue 11, Pages 3010-3013Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.7b00620
Keywords
-
Funding
- National Natural Science Foundation of China [81422054, 3171101305]
- Guangdong Natural Science Funds for Distinguished Young Scholar [S2013050014287]
- Guangdong Special Support Program [2016TX03R280]
- Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme
- K. C. Wong Education Foundation
- Ministry of Education of the People's Republic of China [B13038]
- State Key Laboratory of Pharmaceutical Biotechnology (Nanjing University) [KF-GN-201412]
Ask authors/readers for more resources
Houttuynoid M (1), a new houttuynoid, and the related known compound houttuynoid A (2) were isolated from Houttuynia cordata. Their structures were defined using NMR data analysis, HR-MSn experiment, and chemical derivatization: Houttuynoid M is the first example of a houttuynoid with a bis-houttuynin chain tethered to a flavonoid core. A putative biosynthetic pathway of houttuynoid M (1) is proposed. The anti-herpes simplex virus (anti-HSV) activities of 1 and 2 (IC50 values of 17.72 and 12.42 mu M, respectively) were evaluated using a plaque formation assay with acyclovir as the positive control.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available