Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2

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Title
Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2
Authors
Keywords
tralokinumab, crystal structure, antibody–antigen complex, mutagenesis, antibody structure
Journal
JOURNAL OF MOLECULAR BIOLOGY
Volume 429, Issue 2, Pages 208-219
Publisher
Elsevier BV
Online
2016-12-10
DOI
10.1016/j.jmb.2016.12.005

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