Unraveling new functions of superoxide dismutase using yeast model system: Beyond its conventional role in superoxide radical scavenging

Overexpression of human SOD1 in VDAC1-less yeast restores mitochondrial functionality modulating beta-barrel outer membrane protein genes

(2016) Andrea Magrì et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Expanding roles of superoxide dismutases in cell regulation and cancer

(2016) Meixia Che et al.   DRUG DISCOVERY TODAY

Yap1 and Skn7 genetically interact with Rad51 in response to oxidative stress and DNA double-strand break in Saccharomyces cerevisiae

(2016) Dae Gwan Yi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanisms of a novel anticancer therapeutic strategy involving atmospheric pressure plasma-mediated apoptosis and DNA strand break formation

(2015) Woo-Hyun Chung   ARCHIVES OF PHARMACAL RESEARCH

Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma

(2015) B. R. O'Leary et al.   CLINICAL CANCER RESEARCH

Coping With Oxidative Stress. The Yeast Model

(2015) Maria de la Torre-Ruiz et al.   CURRENT DRUG TARGETS

Extracellular Superoxide Dismutase Protects against Proteinuric Kidney Disease

(2015) R. J. Tan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells

(2015) Babu V. Sajesh et al.   Oncotarget

Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons

(2014) Hong Chen et al.   Cell Stem Cell

SOD2 to SOD1 Switch in Breast Cancer

(2014) Luena Papa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology

(2014) Rosie K. A. Bunton-Stasyshyn et al.   NEUROSCIENTIST

Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance

(2014) Chi Kwan Tsang et al.   Nature Communications

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration

(2013) Amit R. Reddi et al.   CELL

Synthetic Lethal Targeting of Superoxide Dismutase 1 Selectively Kills RAD54B -Deficient Colorectal Cancer Cells

(2013) Babu V. Sajesh et al.   GENETICS

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

(2013) Hyung-Jun Kim et al.   NATURE GENETICS

Manganese Superoxide Dismutase (Sod2) and Redox-Control of Signaling Events That Drive Metastasis

(2012) Nadine Hempel et al.   Anti-Cancer Agents in Medicinal Chemistry

Metallation state of human manganese superoxide dismutase expressed in Saccharomyces cerevisiae

(2012) Mei M. Whittaker et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Saccharomyces cerevisiae as a model system to study the response to anticancer agents

(2012) Renata Matuo et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Yap1: A DNA damage responder in Saccharomyces cerevisiae

(2012) Lori A. Rowe et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Superoxide dismutases: Ancient enzymes and new insights

(2011) Anne-Frances Miller   FEBS LETTERS

Metabolic alterations in yeast lacking copper–zinc superoxide dismutase

(2011) Sadaf Sehati et al.   FREE RADICAL BIOLOGY AND MEDICINE

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines

(2011) R. Somwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In yeast redistribution of Sod1 to the mitochondrial intermembrane space provides protection against respiration derived oxidative stress

(2010) Christine Klöppel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse

(2010) Lindsey R. Fischer et al.   BRAIN

MnSOD drives neuroendocrine differentiation, androgen independence, and cell survival in prostate cancer cells

(2010) Isabel Quiros-Gonzalez et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nickel superoxide dismutase: structural and functional roles of Cys2 and Cys6

(2010) Kelly C. Ryan et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Aggregation of Copper–Zinc Superoxide Dismutase in Familial and Sporadic ALS

(2009) Madhuri Chattopadhyay et al.   ANTIOXIDANTS & REDOX SIGNALING

Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS)

(2009) Kathryn Volkening et al.   BRAIN RESEARCH

Regulation of superoxide dismutase genes: Implications in disease

(2009) Lu Miao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

In silicoanalysis of nickel containing superoxide dismutase evolution and regulation

(2009) Astrid Schmidt et al.   JOURNAL OF BASIC MICROBIOLOGY

The Right to Choose: Multiple Pathways for Activating Copper,Zinc Superoxide Dismutase

(2009) Jeffry M. Leitch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Structure of Human Extracellular Copper–Zinc Superoxide Dismutase at 1.7 Å Resolution: Insights into Heparin and Collagen Binding

(2009) Svetlana V. Antonyuk et al.   JOURNAL OF MOLECULAR BIOLOGY

The kynurenines are associated with oxidative stress, inflammation and the prevalence of cardiovascular disease in patients with end-stage renal disease

(2008) Krystyna Pawlak et al.   ATHEROSCLEROSIS

The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension

(2008) Luciana Esposito et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

DNA damage-induced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiae

(2008) Lori A. Rowe et al.   FREE RADICAL BIOLOGY AND MEDICINE