Weight-sparing effect of insulin detemir: a consequence of central nervous system-mediated reduced energy intake?

Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin

(2015) Denovan P. Begg et al.   DIABETES

Central Insulin Administration Improves Whole-Body Insulin Sensitivity via Hypothalamus and Parasympathetic Outputs in Men

(2014) M. Heni et al.   DIABETES

Basal Insulin Peglispro Demonstrates Preferential Hepatic Versus Peripheral Action Relative to Insulin Glargine in Healthy Subjects

(2014) Robert R. Henry et al.   DIABETES CARE

Effects of Insulin Detemir and NPH Insulin on Body Weight and Appetite-Regulating Brain Regions in Human Type 1 Diabetes: A Randomized Controlled Trial

(2014) Larissa W. van Golen et al.   PLoS One

Insulin Detemir Causes Lesser Weight Gain in Comparison to Insulin Glargine: Role on Hypothalamic NPY and Galanin

(2014) Mohammad Ishraq Zafar et al.   Journal of Diabetes Research

Cerebral Blood Flow and Glucose Metabolism in Appetite-Related Brain Regions in Type 1 Diabetic Patients After Treatment With Insulin Detemir and NPH Insulin: A randomized controlled crossover trial

(2013) L. W. van Golen et al.   DIABETES CARE

Standards of Medical Care in Diabetes--2014

(2013)   DIABETES CARE

A comparison of insulin detemir and neutral protamine Hagedorn (isophane) insulin in the treatment of diabetes: a systematic review

(2013) B. M. Frier et al.   DIABETES OBESITY & METABOLISM

Hepatoselectivity and the evolution of insulin

(2013) R. Herring et al.   DIABETES OBESITY & METABOLISM

Monounsaturated Fatty Acids Prevent the Aversive Effects of Obesity on Locomotion, Brain Activity, and Sleep Behavior

(2012) T. Sartorius et al.   DIABETES

Postprandial Administration of Intranasal Insulin Intensifies Satiety and Reduces Intake of Palatable Snacks in Women

(2012) M. Hallschmid et al.   DIABETES

Insulin Degludec Versus Insulin Glargine in Insulin-Naive Patients With Type 2 Diabetes: A 1-year, randomized, treat-to-target trial (BEGIN Once Long)

(2012) B. Zinman et al.   DIABETES CARE

Insulin analogues in children with Type 1 diabetes: a 52-week randomized clinical trial

(2012) N. Thalange et al.   DIABETIC MEDICINE

Nasal insulin changes peripheral insulin sensitivity simultaneously with altered activity in homeostatic and reward-related human brain regions

(2012) M. Heni et al.   DIABETOLOGIA

Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation

(2011) F. Karpe et al.   DIABETES

Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance

(2011) J. Hirvonen et al.   DIABETES

Insulin Detemir Reduces Weight Gain as a Result of Reduced Food Intake in Patients With Type 1 Diabetes

(2011) S. Zachariah et al.   DIABETES CARE

Comparison of insulins detemir and glargine: effects on glucose disposal, hepatic glucose release and the central nervous system

(2011) M. C. Moore et al.   DIABETES OBESITY & METABOLISM

Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients

(2011) K. V. Hendriksen et al.   DIABETOLOGIA

fMRI reactivity to high-calorie food pictures predicts short- and long-term outcome in a weight-loss program

(2011) Donna L. Murdaugh et al.   NEUROIMAGE

Changes in Brain Activity After a Diet-Induced Obesity

(2011) David Val-Laillet et al.   Obesity

Insulin detemir attenuates food intake, body weight gain and fat mass gain in diet-induced obese Sprague–Dawley rats

(2011) J M Rojas et al.   Nutrition & Diabetes

Euglycemic Infusion of Insulin Detemir Compared With Human Insulin Appears to Increase Direct Current Brain Potential Response and Reduces Food Intake While Inducing Similar Systemic Effects

(2010) M. Hallschmid et al.   DIABETES

Obese children show hyperactivation to food pictures in brain networks linked to motivation, reward and cognitive control

(2010) A S Bruce et al.   INTERNATIONAL JOURNAL OF OBESITY

Insulin detemir is not transported across the blood–brain barrier

(2010) William A. Banks et al.   PEPTIDES

Differential effects of insulin detemir and neutral protamine Hagedorn (NPH) insulin on hepatic glucose production and peripheral glucose uptake during hypoglycaemia in type 1 diabetes

(2009) F. Smeeton et al.   DIABETOLOGIA

Lights and shadows of insulin treatment seen by a senior diabetologist

(2009) Domenico Andreani   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

The Insulin Effect on Cerebrocortical Theta Activity Is Associated with Serum Concentrations of Saturated Nonesterified Fatty Acids

(2009) Otto Tschritter et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

(2008) Kelly A. Posey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reduced Weight Gain with Insulin Detemir Compared to NPH Insulin Is Not Explained by a Reduction in Hypoglycemia

(2008) Melanie J. Davies et al.   Diabetes Technology & Therapeutics

Risk of cardiovascular disease and mortality in overweight and obese patients with type 2 diabetes: an observational study in 13,087 patients

(2008) K. Eeg-Olofsson et al.   DIABETOLOGIA

Insulin detemir improves glycaemic control without weight gain in insulin-naïve patients with type 2 diabetes: subgroup analysis from the PREDICTIVETM study

(2008) A. Dornhorst et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE