Article
Endocrinology & Metabolism
John Punnose, Rajeev Kumar Malhotra, Komal Sukhija, M. Rashika Rijhwani, Naimaa Choudhary, Asha Sharma, Prassan Vij, Pinky Bahl
Summary: Asian Indian women diagnosed with gestational diabetes (GDM) before 24 weeks of gestation have a higher risk for adverse pregnancy outcomes compared to those diagnosed at or after 24 weeks or without GDM.
Review
Medicine, General & Internal
Lore Raets, Kaat Beunen, Katrien Benhalima
Summary: The incidence of gestational diabetes mellitus (GDM) is increasing worldwide, and screening and treatment in early pregnancy still lack consensus. Observational studies show varying results in detecting GDM early, with ongoing large RCTs to determine appropriate strategies and benefits. There is also limited evidence on the sensitivity of HbA1c in early pregnancy, requiring further research.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Alice Ronco, Sofia Roero, Silvana Arduino, Arianna Arese, Isabella Ferrando, Gabriella Scaltrito, Viola Casula, Teresa Fea, Mattia Mazza, Carlotta Bossotti, Roberto Zizzo, Alberto Revelli
Summary: This study analyzed the specific effects of gestational diabetes mellitus (GDM) on twin pregnancy outcomes. The results showed that compared to GDM singleton pregnancies, GDM twins had higher rates of preeclampsia, cesarean section, and neonatal hypoglycemia. Compared to twin pregnancies without GDM, women with GDM twins were older, had higher BMI, had a higher incidence of large-for-gestational-age (LGA) newborns, and a lower incidence of low APGAR scores. Overall, GDM does not worsen outcomes of twin pregnancy.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Aiqi Yin, Fuying Tian, Xiaoxia Wu, Yixuan Chen, Kan Liu, Jianing Tong, Xiaonian Guan, Huafan Zhang, Linlin Wu, Jianmin Niu
Summary: This study evaluated the effect of weight gain in different trimesters on the risk of gestational diabetes mellitus (GDM). The results showed that insufficient weight gain in early pregnancy and excessive weight gain in middle pregnancy were associated with an increased risk of GDM. Strict control of weight gain in early pregnancy and sufficient nutrition in middle pregnancy are necessary.
CHINESE MEDICAL JOURNAL
(2022)
Article
Endocrinology & Metabolism
E. Yefet, E. Jeda, A. Yossef, M. Massalha, A. Tzur, Z. Nachum
Summary: This study aimed to examine the effect of early-onset gestational diabetes mellitus (GDM) on unfavorable pregnancy outcomes. The results showed that the risk for fetal malformations was similar between early-onset, late-onset, and third trimester GDM. However, early-onset GDM was associated with a higher risk of neonatal hypoglycemia and shoulder dystocia.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Multidisciplinary Sciences
Qing-Xiang Zheng, Hai-Wei Wang, Xiu-Min Jiang, Yan Lin, Gui-Hua Liu, Mian Pan, Li Ge, Xiao-Qian Chen, Jing-Ling Wu, Xiao-Yun Zhang, Yu-Qing Pan, Hong-Gu He
Summary: This study aimed to determine the ranges of gestational weight gain (GWG) in Chinese women with gestational diabetes mellitus (GDM) and investigate the associations between prepregnancy body mass index (BMI), GWG, and maternal-infant adverse outcomes. The findings revealed that the ranges of GWG in Chinese women with GDM were different from the National Academy of Medicine's recommendation, and GDM women with high prepregnancy BMI and excessive GWG were associated with higher risks of adverse outcomes for both the mother and the infant.
SCIENTIFIC REPORTS
(2022)
Article
Endocrinology & Metabolism
Chiara Giuliani, Laura Sciacca, Nicolina Di Biase, Andrea Tumminia, Agostino Milluzzo, Antongiulio Faggiano, Francesca Romana Amorosi, Alessio Convertino, Olimpia Bitterman, Camilla Festa, Angela Napoli
Summary: GDM has a high recurrence rate in pregnant women, with an increase in pregravid BMI for women with recurrent GDM between two pregnancies.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2022)
Article
Endocrinology & Metabolism
Sayuri Nakanishi, Shigeru Aoki, Junko Kasai, Ryosuke Shindo, Soichiro Obata, Yoshimi Hasegawa, Aya Mochimaru, Kentaro Kurasawa, Etsuko Miyagi
Summary: This study aimed to verify the effectiveness of intervention in early pregnancy for women with early-onset GDM. The results showed that early intervention did not improve pregnancy outcomes and even increased the rate of small for gestational age (SGA) infants.
BMJ OPEN DIABETES RESEARCH & CARE
(2023)
Article
Endocrinology & Metabolism
Ping Hu, Xiuyi Chen, Xufeng Chu, Mengran Fan, Yi Ye, Yi Wang, Maozhen Han, Xue Yang, Jiaying Yuan, Li Zha, Bin Zhao, Chun-Xia Yang, Xiao-Rong Qi, Kang Ning, Justin Debelius, Weimin Ye, Bo Xiong, Xiong-Fei Pan, An Pan
Summary: The study aimed to evaluate the association between gut bacterial biomarkers during early pregnancy and the risk of gestational diabetes mellitus (GDM) in Chinese pregnant women. Results showed that gut microbiota in early pregnancy was linked to subsequent GDM risk, with beneficial microorganisms inversely related to GDM incidence and pathogenic members associated with higher incident GDM risk and correlated with glucose levels on OGTT.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Public, Environmental & Occupational Health
Dongxin Lin, Dazhi Fan, Pengsheng Li, Gengdong Chen, Jiaming Rao, Zixing Zhou, Huishan Zhang, Xin Luo, Huiting Ma, Jingping Feng, Demei Lu, Lijuan Wang, Shiyan Lan, Caihong Luo, Xiaoling Guo, Zhengping Liu
Summary: The study found that twin pregnancies with GDM had comparable pregnancy and neonatal outcomes to those without GDM. Twin pregnancies with GDM and adequate prenatal care have similar perinatal outcomes to those without diabetes.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Medical Laboratory Technology
Xiaoshi Sun, He Sun, Ping Li
Summary: Gestational diabetes mellitus (GDM) is the most common cause of hyperglycemia during pregnancy, with direct impact on obstetric outcomes and long-term maternal and child health. Recent studies have shown a connection between circulating inflammatory cells, platelets, and the development of GDM and adverse pregnancy outcomes.
CLINICA CHIMICA ACTA
(2021)
Article
Endocrinology & Metabolism
Chen Zhang, Lilian Bai, Kuan Sun, Guolian Ding, Xinmei Liu, Yanting Wu, Hefeng Huang
Summary: This study examines the combined effects of FT4 and TG on the prevalence of GDM in early pregnancy and finds that low TG levels are an important mediator in reducing the risk of GDM.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Kymberleigh A. Pagel, Hoyin Chu, Rashika Ramola, Rafael F. Guerrero, Judith H. Chung, Samuel Parry, Uma M. Reddy, Robert M. Silver, Jonathan G. Steller, Lynn M. Yee, Ronald J. Wapner, Matthew W. Hahn, Sriraam Natarajan, David M. Haas, Predrag Radivojac
Summary: This cohort study found that the addition of polygenic risk scores (PRS) was associated with the stratified risk of gestational diabetes (GD) diagnosis among high-risk patient subgroups, suggesting the benefits of targeted PRS ascertainment to encourage early intervention.
Review
Endocrinology & Metabolism
Matladi Masete, Stephanie Dias, Nompumelelo Malaza, Sumaiya Adam, Carmen Pheiffer
Summary: Maternal diabetes, especially pregestational type 1 and type 2 diabetes, is associated with more frequent and severe pregnancy complications compared to gestational diabetes. Recent studies have shown the potential role of miRNAs in the pathophysiology of pregnancy-related disorders, including diabetes. However, there is a lack of miRNA profiling studies in pregnancies complicated by pregestational diabetes, highlighting the need for further research in this area.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Yunzhen Ye, Yu Xiong, Qiongjie Zhou, Xirong Xiao, Xiaotian Li
Summary: There is an association between early-pregnancy intermediate hyperglycemia and adverse pregnancy outcomes among women without gestational diabetes. Women with intermediate hyperglycemia in early pregnancy have higher risks for adverse maternal-fetal outcomes, even with normal future OGTTs, and they tend to have higher age and body mass index.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Arianne N. Sweeting, Glynis P. Ross, Jon Hyett, Lynda Molyneaux, Kris Tan, Maria Constantino, Anna Jane Harding, Jencia Wong
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2017)
Article
Obstetrics & Gynecology
Arianne N. Sweeting, Jencia Wong, Heidi Appelblom, Glynis P. Ross, Heikki Kouru, Paul F. Williams, Mikko Sairanen, Jon A. Hyett
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2018)
Editorial Material
Endocrinology & Metabolism
Arianne N. Sweeting, Glynis P. Ross, Jon Hyett, Jencia Wong
LANCET DIABETES & ENDOCRINOLOGY
(2017)
Review
Endocrinology & Metabolism
Susan G. Gray, Arianne N. Sweeting, Treasure M. Mcguire, Neale Cohen, Glynis P. Ross, Peter J. Little
JOURNAL OF DIABETES
(2018)
Article
Obstetrics & Gynecology
Arianne N. Sweeting, Albert Hsieh, Jencia Wong, Glynis P. Ross
Summary: The study compared the efficacy of subcutaneous insulin (SC-I) and intravenous insulin (IV-I) protocols on maternal blood glucose levels post-betamethasone administration. Results indicated a potential superiority of the SC-I protocol in controlling blood glucose levels, particularly in women with gestational diabetes.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Nutrition & Dietetics
Roslyn Muirhead, Nathalie Kizirian, Ravin Lal, Kirsten Black, Ann Prys-Davies, Natasha Nassar, Louise Baur, Amanda Sainsbury, Arianne Sweeting, Tania Markovic, Michael Skilton, Jon Hyett, Bradley de Vries, William Tarnow-Mordi, Jennie Brand-Miller, Adrienne Gordon
Summary: The study compared the effectiveness of using partial meal replacement programs and conventional dietary advice for pre-conception weight loss, finding that women using meal replacements lost an average of 5.4% body weight over 10 weeks, which was higher than those receiving traditional dietary advice. Additionally, women using meal replacements were more likely to achieve pregnancy within 12 months after the 10-week intervention.
Review
Nutrition & Dietetics
Arianne Sweeting, Jovana Mijatovic, Grant D. Brinkworth, Tania P. Markovic, Glynis P. Ross, Jennie Brand-Miller, Teri L. Hernandez
Summary: Recent studies suggest that the optimal carbohydrate intake during pregnancy is in the range of 47-70% of total energy intake. Further research is needed to investigate the effects of low carbohydrate diets on pregnant women and fetal development.
Review
Endocrinology & Metabolism
Arianne Sweeting, Jencia Wong, Helen R. Murphy, Glynis P. Ross
Summary: Gestational diabetes mellitus (GDM) refers to abnormal glucose tolerance that occurs during pregnancy and is associated with higher infant birthweight, as well as future maternal and offspring cardiometabolic disease. The prevalence of GDM is increasing globally due to factors such as rising obesity rates in women of reproductive age and revised diagnostic criteria. Although there is a lack of international consensus on the diagnosis of GDM, it is important to recognize it as an early risk factor for type 2 diabetes and cardiovascular disease, considering its long-term complications for both mothers and offspring.
Article
Obstetrics & Gynecology
Radhika Seimon, Nassar Natasha, Francisco J. Schneuer, Gavin Pereira, Adam Mackie, Glynis P. Ross, Arianne N. Sweeting, Sean K. M. Seeho, Samantha L. Hocking
Summary: Induction of labor at 38, 39, and 40 weeks gestation is associated with an increased risk of cesarean section among women with gestational diabetes without specific medical conditions. However, there is no difference in neonatal morbidity or perinatal death between induction and expectant management groups.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2022)