NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury

Inhibition of Hyperhomocysteinemia-Induced Inflammasome Activation and Glomerular Sclerosis by NLRP3 Gene Deletion

(2017) Min Xia et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation

(2016) Sesquile Ramon et al.   AMERICAN JOURNAL OF PATHOLOGY

Resolvin D1 and E1 promote resolution of inflammation in microglial cells in vitro

(2016) C. Rey et al.   BRAIN BEHAVIOR AND IMMUNITY

Resolvin D2 Enhances Postischemic Revascularization While Resolving InflammationClinical Perspective

(2016) Michael J. Zhang et al.   CIRCULATION

Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents AtherosclerosisNovelty and Significance

(2016) Gantsetseg Tumurkhuu et al.   CIRCULATION RESEARCH

N-3 vs. n-6 fatty acids differentially influence calcium signalling and adhesion of inflammatory activated monocytes: impact of lipid rafts

(2016) Martina Barbara Schaefer et al.   INFLAMMATION RESEARCH

Docosahexaenoic acid and palmitic acid reciprocally modulate monocyte activation in part through endoplasmic reticulum stress

(2016) Ryan G. Snodgrass et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease

(2016) Marina Saresella et al.   Molecular Neurodegeneration

Cardiovascular Pathobiology of Inflammasomes: Inflammatory Machinery and Beyond

(2015) Pin-Lan Li   ANTIOXIDANTS & REDOX SIGNALING

Hierarchical Regulation of Wound Healing by NOD-Like Receptors in Cardiovascular Disease

(2015) Nathan A. Bracey et al.   ANTIOXIDANTS & REDOX SIGNALING

Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis

(2015) Yang Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Importance of NLRP3 Inflammasome in Heart Failure

(2015) Brittany Butts et al.   JOURNAL OF CARDIAC FAILURE

Docosahexaenoic acid and eicosapentaenoic acid suppress adhesion molecule expression in human aortic endothelial cells via differential mechanisms

(2015) Chun-Ying Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

NADPH Oxidase-Induced NALP3 Inflammasome Activation Is Driven by Thioredoxin-Interacting Protein Which Contributes to Podocyte Injury in Hyperglycemia

(2015) Pan Gao et al.   Journal of Diabetes Research

Nod-like Receptor Protein 3 (NLRP3) Inflammasome Activation and Podocyte Injury via Thioredoxin-Interacting Protein (TXNIP) during Hyperhomocysteinemia

(2014) Justine M. Abais et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-inflammatory effects of resolvin-D1 on human corneal epithelial cells: in vitro study

(2014) Nir Erdinest et al.   Journal of Inflammation-London

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

(2014) Paul M Peeters et al.   Particle and Fibre Toxicology

Omega-3 Free Fatty Acids Suppress Macrophage Inflammasome Activation by Inhibiting NF-κB Activation and Enhancing Autophagy

(2014) Yolanda Williams-Bey et al.   PLoS One

Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis

(2013) Eun Jeong Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Confusion between protectin D1 (PD1) and its isomer protectin DX (PDX). An overview on the dihydroxy-docosatrienes described to date

(2013) Laurence Balas et al.   BIOCHIMIE

Resolution phase lipid mediators of inflammation: agonists of resolution

(2013) Charles N. Serhan et al.   CURRENT OPINION IN PHARMACOLOGY

Concentrated fish oil (Lovaza®) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW)F1 mice

(2013) Ganesh V Halade et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia

(2013) Justine M. Abais et al.   FREE RADICAL BIOLOGY AND MEDICINE

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Lower NLRP3 inflammasome activity in NAG-1 transgenic mice is linked to a resistance to obesity and increased insulin sensitivity

(2013) Xingya Wang et al.   Obesity

Anti-cancer activity of DHA on gastric cancer—an in vitro and in vivo study

(2013) Haijun Sun et al.   TUMOR BIOLOGY

Paraoxonase 1 and homocysteine metabolism

(2012) Joanna Perła-Kaján et al.   AMINO ACIDS

NADPH Oxidase-Mediated Triggering of Inflammasome Activation in Mouse Podocytes and Glomeruli During Hyperhomocysteinemia

(2012) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: A randomized controlled trial

(2012) Janice K. Kiecolt-Glaser et al.   BRAIN BEHAVIOR AND IMMUNITY

Role of homocysteine in end-stage renal disease

(2012) Chia-Chao Wu et al.   CLINICAL BIOCHEMISTRY

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

(2012) Hye-Mi Lee et al.   DIABETES

Activation of Nod-Like Receptor Protein 3 Inflammasomes Turns on Podocyte Injury and Glomerular Sclerosis in Hyperhomocysteinemia

(2012) Chun Zhang et al.   HYPERTENSION

Further insights about the beneficial effects of n-3 fatty acids in the early molecular events of renal fibrosis in vitro

(2012) Giovanna Priante et al.   JOURNAL OF NEPHROLOGY

Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells

(2012) Xiaoqin Luo et al.   Nutrition & Metabolism

Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson’s disease

(2012) Monika Białecka et al.   Pharmacogenetics and Genomics

Chemopreventive and renal protective effects for docosahexaenoic acid (DHA): implications of CRP and lipid peroxides

(2012) ME El-Mesery et al.   Cell Division

Acid Sphingomyelinase Gene Deficiency Ameliorates the Hyperhomocysteinemia-Induced Glomerular Injury in Mice

(2011) Krishna M. Boini et al.   AMERICAN JOURNAL OF PATHOLOGY

Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia

(2011) Minzhong Yu et al.   EXPERIMENTAL EYE RESEARCH

c-fms blockade reverses glomerular macrophage infiltration and halts development of crescentic anti-GBM glomerulonephritis in the rat

(2011) Yingjie Han et al.   LABORATORY INVESTIGATION

Specialized pro-resolving lipid mediators in the inflammatory response: An update

(2010) Gerard Bannenberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene

(2010) Chun Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Docosahexaenoic Acid-Enriched Fish Oil Attenuates Kidney Disease and Prolongs Median and Maximal Life Span of Autoimmune Lupus-Prone Mice

(2010) G. V. Halade et al.   JOURNAL OF IMMUNOLOGY

Docosahexanoic Acid-Induced Coronary Arterial Dilation: Actions of 17S-Hydroxy Docosahexanoic Acid on K+ Channel Activity

(2010) X. Li et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Fish Oil Supplementation Lowers C-Reactive Protein Levels Independent of Triglyceride Reduction in Patients With End-Stage Renal Disease

(2009) Rodney G. Bowden et al.   NUTRITION IN CLINICAL PRACTICE

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway

(2008) Sharon DeMorrow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Anti-Inflammatory and Proresolving Lipid Mediators

(2008) Charles N. Serhan et al.   Annual Review of Pathology-Mechanisms of Disease