TM6SF2 rs58542926 variant affects postprandial lipoprotein metabolism and glucose homeostasis in NAFLD

Thiazolidinediones and Advanced Liver Fibrosis in Nonalcoholic Steatohepatitis

(2017) Giovanni Musso et al.   JAMA Internal Medicine

TM6SF2 may drive postprandial lipoprotein cholesterol toxicity away from the vessel walls to the liver in NAFLD

(2016) Giovanni Musso et al.   JOURNAL OF HEPATOLOGY

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

(2016) Giovanni Musso et al.   NATURE REVIEWS DRUG DISCOVERY

Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease

(2015) Paola Dongiovanni et al.   HEPATOLOGY

Postprandial lipemia as a cardiometabolic risk factor

(2014) Angela Pirillo et al.   CURRENT MEDICAL RESEARCH AND OPINION

Chronic Reduction of GIP Secretion Alleviates Obesity and Insulin Resistance Under High-Fat Diet Conditions

(2014) D. Nasteska et al.   DIABETES

Lipoprotein subclass metabolism in nonalcoholic steatohepatitis

(2014) Ville T. Männistö et al.   JOURNAL OF LIPID RESEARCH

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

(2014) Oddgeir L Holmen et al.   NATURE GENETICS

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

(2014) H. Mahdessian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of the amount and type of dietary fat on cardiometabolic risk factors and risk of developing type 2 diabetes, cardiovascular diseases, and cancer: a systematic review

(2014) Ursula Schwab et al.   Food & Nutrition Research

Low-density lipoprotein receptors in liver: Old acquaintances and a newcomer

(2013) Ursula Pieper-Fürst et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Very Low Density Lipoprotein Receptor (VLDLR) Expression Is a Determinant Factor in Adipose Tissue Inflammation and Adipocyte-Macrophage Interaction

(2013) Andrew Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions among bone, liver, and adipose tissue predisposing to diabesity and fatty liver

(2013) Giovanni Musso et al.   TRENDS IN MOLECULAR MEDICINE

Adiponectin Corrects High-Fat Diet-Induced Disturbances in Muscle Metabolomic Profile and Whole-Body Glucose Homeostasis

(2012) Y. Liu et al.   DIABETES

Sterol Regulatory Element-Binding Factor 2 (SREBF-2) Predicts 7-Year NAFLD Incidence and Severity of Liver Disease and Lipoprotein and Glucose Dysmetabolism

(2012) G. Musso et al.   DIABETES

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor

(2012) Hyunsun Jo et al.   HEPATOLOGY

Low density lipoprotein receptor-related protein 1 modulates the proliferation and migration of human hepatic stellate cells

(2012) V. Llorente-Cortes et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis

(2012) Giovanni Musso et al.   PROGRESS IN LIPID RESEARCH

Obstructive Sleep Apnea-Hypopnea Syndrome and Nonalcoholic Fatty Liver Disease: Emerging Evidence and Mechanisms

(2012) Giovanni Musso et al.   SEMINARS IN LIVER DISEASE

Genetic modifiers of non-alcoholic fatty liver disease progression

(2011) Quentin M. Anstee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Association of endothelial and oxidative stress with metabolic syndrome and subclinical atherosclerosis: multi-ethnic study of atherosclerosis

(2011) D Vaidya et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity

(2010) Giovanni Musso et al.   ANNALS OF MEDICINE

Effects of peripheral administration of synthetic human glucose-dependent insulinotropic peptide (GIP) on energy expenditure and subjective appetite sensations in healthy normal weight subjects and obese patients with type 2 diabetes

(2009) C. Daousi et al.   CLINICAL ENDOCRINOLOGY

Lipoprotein metabolism mediates the association of MTP polymorphism with β-cell dysfunction in healthy subjects and in nondiabetic normolipidemic patients with nonalcoholic steatohepatitis

(2009) Giovanni Musso et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY