Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation

The Perilipins: Major Cytosolic Lipid Droplet–Associated Proteins and Their Roles in Cellular Lipid Storage, Mobilization, and Systemic Homeostasis

(2016) Alan R. Kimmel et al.   Annual Review of Nutrition

Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of known inhibitors

(2015) Jose Iglesias et al.   JOURNAL OF LIPID RESEARCH

The Interplay of Protein Kinase A and Perilipin 5 Regulates Cardiac Lipolysis

(2014) Nina M. Pollak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of Plin4 downregulates Plin5 and reduces cardiac lipid accumulation in mice

(2013) Weiqin Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Perilipins: Lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection

(2013) Carole Sztalryd et al.   BIOCHIMIE

Fatty acids regulate perilipin5 in muscle by activating PPARδ

(2013) Christian Bindesbøll et al.   JOURNAL OF LIPID RESEARCH

Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease

(2013) James L. McManaman et al.   JOURNAL OF LIPID RESEARCH

Development of small-molecule inhibitors targeting adipose triglyceride lipase

(2013) Nicole Mayer et al.   Nature Chemical Biology

Regulation of energy metabolism by long-chain fatty acids

(2013) Manabu T. Nakamura et al.   PROGRESS IN LIPID RESEARCH

Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase

(2012) Siril S. Bakke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

(2012) Jian Ye et al.   BMC BIOINFORMATICS

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

(2012) M. Bosma et al.   DIABETES

Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation

(2012) Kenta Kuramoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets

(2012) Kai Hsieh et al.   JOURNAL OF CELL SCIENCE

Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58

(2012) Pierre-Marie Badin et al.   JOURNAL OF LIPID RESEARCH

PPARs: Fatty acid sensors controlling metabolism

(2012) Lars la Cour Poulsen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Role of intramyocelluar lipids in human health

(2012) Paul M. Coen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mechanisms of Gene Regulation by Fatty Acids

(2012) Anastasia Georgiadi et al.   Advances in Nutrition

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

Obesity-associated insulin resistance in skeletal muscle: Role of lipid accumulation and physical inactivity

(2011) Kristin Eckardt et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharide-induced lipolysis in human adipocytes

(2010) Jean Grisouard et al.   Innate Immunity

Metabolic switching of human myotubes is improved by n-3 fatty acids

(2010) N. P. Hessvik et al.   JOURNAL OF LIPID RESEARCH

Absence of adipose differentiation related protein upregulates hepatic VLDL secretion, relieves hepatosteatosis, and improves whole body insulin resistance in leptin-deficient mice

(2010) Benny Hung-Junn Chang et al.   JOURNAL OF LIPID RESEARCH

The Randle cycle revisited: a new head for an old hat

(2009) Louis Hue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

LXRβ is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux

(2009) N. P. Hessvik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores

(2009) Perry E. Bickel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Adipophilin distribution and colocalisation with lipid droplets in skeletal muscle

(2009) Christopher S. Shaw et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Higher intramuscular triacylglycerol in women does not impair insulin sensitivity and proximal insulin signaling

(2009) Louise Høeg et al.   JOURNAL OF APPLIED PHYSIOLOGY

Adipocyte Differentiation-Related Protein and OXPAT in Rat and Human Skeletal Muscle: Involvement in Lipid Accumulation and Type 2 Diabetes Mellitus

(2009) Ronnie Minnaard et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins: TABLE 1.

(2009) Alan R. Kimmel et al.   JOURNAL OF LIPID RESEARCH

Inhibition of ADRP prevents diet-induced insulin resistance

(2008) Gladys M. Varela et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Consequences of Lipid Droplet Coat Protein Downregulation in Liver Cells: Abnormal Lipid Droplet Metabolism and Induction of Insulin Resistance

(2008) M. Bell et al.   DIABETES

Determinants of intramyocellular triglyceride turnover: implications for insulin sensitivity

(2007) Cédric Moro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM