Article
Developmental Biology
Olivia Spead, Cory J. Weaver, Trevor Moreland, Fabienne E. Poulain
Summary: The study used a zebrafish model to dynamically analyze retinotectal mapping in vivo, revealing that the antero-posterior retinotopic map forms early but remains dynamic, with nasal and temporal retinal axons expanding their projection domains over time. The refinement of nasal retinal projections was shown to require the adhesion molecule Contactin 2.
Article
Chemistry, Physical
Miles F. Beaux, Reuben J. Peterson, Igor O. Usov
Summary: Atomic force microscopy was used to map the topography and qualitative mechanical characteristics of gallium-stabilized delta-phase plutonium coupons. The initial rough and heterogeneous surface of plutonium was observed, along with distinct striation patterns in qualitative nanomechanical mapping. Investigation suggested that the striations were not measurement artifacts or plutonium-specific features, and were influenced by mechanical working of the surface.
SURFACES AND INTERFACES
(2021)
Article
Medicine, General & Internal
Yu Xiao, Zhigang Song, Shuangmei Zou, Yan You, Jie Cui, Shuhao Wang, Calvin Ku, Xi Wu, Xiaowei Xue, Wenqi Han, Weixun Zhou
Summary: An AI-assisted system was developed to help pathologists complete the ESD topographic mapping process rapidly and accurately, saving time and improving precision.
FRONTIERS IN MEDICINE
(2022)
Article
Pharmacology & Pharmacy
Peishan Qiu, Daojiang Li, Cong Xiao, Fei Xu, Xiaoyu Chen, Ying Chang, Lan Liu, Lei Zhang, Qiu Zhao, Yuhua Chen
Summary: The extent of gut inflammation depends on the gut barrier's integrity and enteric neuroimmune interactions. The role of Eph/ephrin signaling in regulating gut homeostasis, inflammation, neuroimmune interactions, and pain pathways is critical. Targeting the Eph/ephrin system provides innovative treatments for gut inflammation disorders.
PHARMACOLOGICAL RESEARCH
(2023)
Article
Multidisciplinary Sciences
K. H. Brian Lam, Alberto J. Leon, Weili Hui, Sandy Che-Eun Lee, Ihor Batruch, Kevin Faust, Almos Klekner, Gabor Hutoczki, Marianne Koritzinsky, Maxime Richer, Ugljesa Djuric, Phedias Diamandis
Summary: This study utilized mass spectrometry to align protein abundance levels with distinct histologic patterns in glioblastoma, proposing diverse molecular programs within regional tumor compartments and defining two distinct proteogenomic programs, MYC- and KRAS-axis. Furthermore, differential drug sensitivities and chemoresistance in glioblastoma cell lines with enhanced KRAS programs were highlighted, suggesting potential insights for targeting heterogeneity and overcoming therapy resistance.
NATURE COMMUNICATIONS
(2022)
Article
Cell Biology
Michael P. Vu, Catherine Cheng
Summary: The eye lens plays a crucial role in focusing light onto the retina, while cataracts are a major cause of blindness worldwide. Recent studies have shown the importance of Eph-ephrin bidirectional signaling in maintaining lens transparency. This study investigated the expression of Eph receptors and ephrin ligands in different cell fractions of the lens, revealing the presence of multiple receptor-ligand pairs that may contribute to lens homeostasis.
Article
Agriculture, Multidisciplinary
Bingxin Yan, Guangwei Wu, Yuejin Xiao, Hebo Mei, Zhijun Meng
Summary: The study designed a seed mapping system for corn planters and found that the seed firmer significantly reduces distance deviation and increases location quality index, while the limiting plate has no significant impact. Operation speed and seed spacing have a significant effect on the mapping accuracy, while the GPS frequency has less influence.
COMPUTERS AND ELECTRONICS IN AGRICULTURE
(2021)
Article
Remote Sensing
He Yin, Bin Tan, David Frantz, Volker C. C. Radeloff
Summary: In mountainous environments, topographic correction is necessary for accurate land cover classification. This study investigates the effectiveness of two topographic correction approaches that integrate atmospheric and topographic correction, and the improvements in classification accuracy when using topographically corrected imagery and additional terrain information. The results show that topographic correction significantly improves classification accuracy, and the physical model performs best among the tested methods.
INTERNATIONAL JOURNAL OF APPLIED EARTH OBSERVATION AND GEOINFORMATION
(2022)
Article
Multidisciplinary Sciences
Yuxuan Cai, Shir Hofstetter, Jelle van Dijk, Wietske Zuiderbaan, Wietske van der Zwaag, Ben M. Harvey, Serge O. Dumoulin
Summary: This study utilized 7T fMRI and biologically-inspired analyses to uncover a network of neural populations tuned to both small and large numerosities, organized within the same topographic maps. The results demonstrate a continuum of numerosity preferences that progressively cover both the subitizing range and beyond within the same numerosity map, suggesting a single neural mechanism. The authors hypothesize that differences in map properties, such as cortical magnification and tuning width, underlie known differences in behavior.
NATURE COMMUNICATIONS
(2021)
Article
Engineering, Electrical & Electronic
Zhiteng Li, Jiannan Zhao, Xiang Zhou, Shengxian Wei, Pei Li, Feng Shuang
Summary: Intelligent drones have significant applications in rescue, inspection, agriculture, etc. Understanding the surroundings is crucial for autonomous tasks, but integrating localization, reconstruction, and segmentation is challenging for power-limited systems like UAVs. To address this, a real-time semantic mapping system is proposed to help power-limited UAVs understand their location and surroundings.
Article
Optics
Sungsam Kang, Renjie Zhou, Marten Brelen, Heather K. Mak, Yuechuan Lin, Peter T. C. So, Zahid Yaqoob
Summary: Researchers report a new speckle diffraction tomography (SDT) approach that can image thick biological specimens with high resolution. By rejecting multiple-scattering background and considering specimen-induced aberrations, SDT achieves depth-resolved refractive index maps. Using SDT, they successfully imaged red blood cells and quantified their membrane fluctuations, as well as performed volumetric imaging of cornea inside an ex vivo rat eye.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Article
Automation & Control Systems
Jianxing Li, Shijing Zhang, Jie Deng, Yingxiang Liu
Summary: This work proposes a high-resolution focusing mechanism using a stepping piezoelectric actuator with bending-bending hybrid actuating units. A piezoelectric autofocus system based on a visual feedback algorithm is established, and a microscopic observation demonstration proves the feasibility of the focusing mechanism. This work provides new ideas and schemes for the design of various microscopes.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2023)
Review
Biochemistry & Molecular Biology
Iason Psilopatis, Eleni Souferi-Chronopoulou, Kleio Vrettou, Constantinos Troungos, Stamatios Theocharis
Summary: EPHs/ephrins appear to be promising treatment targets in the future for breast cancer, with EPHA2 being the most studied target.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Engineering, Multidisciplinary
Chuanliu Fan, Junyi Hou, Lei Yu
Summary: By optimizing IMU propagation strategies and marginalizing frames, this method improves the accuracy of 3D reconstruction. Combining four-level quadtree estimation of depth and map reconstruction, experimental results show that this method outperforms others on public datasets.
Review
Forestry
Felipe Vasquez, Ania Cravero, Manuel Castro, Patricio Acevedo
Summary: Wildfires pose significant environmental and economic challenges, necessitating the selection of appropriate technologies and decision support systems. Research shows that using different types of DSS can solve problems related to wildfire detection, prediction, prevention, and monitoring, but there are still many challenges to be addressed in real-world applications.