Animal Models for Studying Triazole Resistance in Aspergillus fumigatus

Voriconazole-Susceptible and Voriconazole-ResistantAspergillus fumigatusCoinfection

(2016) Eva Kolwijck et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pharmacokinetics and Concentration-Dependent Efficacy of Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis

(2016) Vidmantas Petraitis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Animal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents

(2016) Miao Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America

(2016) Thomas F. Patterson et al.   CLINICAL INFECTIOUS DISEASES

ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients

(2016) Frederic Tissot et al.   HAEMATOLOGICA

Pharmacodynamics for antifungal drug development: an approach for acceleration, risk minimization and demonstration of causality

(2016) William Hope et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Delay of antifungal therapy influences the outcome of invasive aspergillosis in experimental models of infection

(2016) Francesco Barchiesi et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

PCR-based detection of Aspergillus fumigatus Cyp51A mutations on bronchoalveolar lavage: a multicentre validation of the AsperGenius assay ® in 201 patients with haematological disease suspected for invasive aspergillosis

(2016) G. M. Chong et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In-host adaptation and acquired triazole resistance in Aspergillus fumigatus : a dilemma for clinical management

(2016) Paul E Verweij et al.   LANCET INFECTIOUS DISEASES

ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients

(2016) Frederic Tissot et al.   HAEMATOLOGICA

Mechanisms of echinocandin antifungal drug resistance

(2015) David S. Perlin   Annals of the New York Academy of Sciences

Pharmacodynamics of Isavuconazole in an Aspergillus fumigatus Mouse Infection Model

(2015) Seyedmojtaba Seyedmousavi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Environmental Isolates of Azole-Resistant Aspergillus fumigatus in Germany

(2015) Oliver Bader et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole Resistance inAspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?

(2015) Paul E. Verweij et al.   CLINICAL INFECTIOUS DISEASES

International expert opinion on the management of infection caused by azole-resistant Aspergillus fumigatus

(2015) Paul E. Verweij et al.   DRUG RESISTANCE UPDATES

Emergence of azole-resistant invasive aspergillosis in HSCT recipients in Germany

(2015) J. Steinmann et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

First Detection of TR34 L98H and TR46 Y121F T289A Cyp51 Mutations in Aspergillus fumigatus Isolates in the United States

(2015) Nathan P. Wiederhold et al.   JOURNAL OF CLINICAL MICROBIOLOGY

High-Level Pan-Azole-Resistant Aspergillosis: TABLE 1

(2015) Jakko van Ingen et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Posaconazole Prophylaxis in Experimental Azole-Resistant Invasive Pulmonary Aspergillosis

(2014) Seyedmojtaba Seyedmousavi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Animal models of invasive aspergillosis for drug discovery

(2014) Caroline Paulussen et al.   DRUG DISCOVERY TODAY

The role of azoles in the management of azole-resistant aspergillosis: From the bench to the bedside

(2014) Seyedmojtaba Seyedmousavi et al.   DRUG RESISTANCE UPDATES

Exploring azole antifungal drug resistance in Aspergillus fumigatus with special reference to resistance mechanisms

(2014) Anuradha Chowdhary et al.   Future Microbiology

Concomitant occurrence of itraconazole-resistant and -susceptible strains of Aspergillus fumigatus in routine cultures

(2014) Suhail Ahmad et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pharmacodynamics and Dose-Response Relationships of Liposomal Amphotericin B against Different Azole-Resistant Aspergillus fumigatus Isolates in a Murine Model of Disseminated Aspergillosis

(2013) Seyedmojtaba Seyedmousavi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isavuconazole Pharmacodynamic Target Determination for Candida Species in anIn VivoMurine Disseminated Candidiasis Model

(2013) Alexander J. Lepak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Differential expression of ATP-binding cassette and/or major facilitator superfamily class efflux pumps contributes to voriconazole resistance in Aspergillus flavus

(2013) S. Krishnan Natesan et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Major variations inAspergillus fumigatusarising within aspergillomas in chronic pulmonary aspergillosis

(2013) S. J. Howard et al.   MYCOSES

Posaconazole Pharmacodynamic Target Determination against Wild-Type andCyp51Mutant Isolates of Aspergillus fumigatus in anIn VivoModel of Invasive Pulmonary Aspergillosis

(2012) Alexander J. Lepak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacodynamics of Anidulafungin against Clinical Aspergillus fumigatus Isolates in a Nonneutropenic Murine Model of Disseminated Aspergillosis

(2012) Seyedmojtaba Seyedmousavi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging

(2012) Milos Petrik et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Efficacy and pharmacodynamics of voriconazole combined with anidulafungin in azole-resistant invasive aspergillosis

(2012) S. Seyedmousavi et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Rapid Induction of Multiple Resistance Mechanisms in Aspergillus fumigatus during Azole Therapy: a Case Study and Review of the Literature

(2011) Simone M. T. Camps et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Observational Study of the Clinical Efficacy of Voriconazole and Its Relationship to Plasma Concentrations in Patients

(2011) Peter F. Troke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-frequency Triazole Resistance Found In Nonculturable Aspergillus fumigatus from Lungs of Patients with Chronic Fungal Disease

(2011) David W. Denning et al.   CLINICAL INFECTIOUS DISEASES

Pharmacokinetics and Pharmacodynamics of Posaconazole for Invasive Pulmonary Aspergillosis: Clinical Implications for Antifungal Therapy

(2011) Susan J. Howard et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of cyp51A Mutations on the Pharmacokinetic and Pharmacodynamic Properties of Voriconazole in a Murine Model of Disseminated Aspergillosis

(2010) E. Mavridou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole Resistance Profile of Amino Acid Changes in Aspergillus fumigatus CYP51A Based on Protein Homology Modeling

(2010) E. Snelders et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Initial 96 Hours of Invasive Pulmonary Aspergillosis: Histopathology, Comparative Kinetics of Galactomannan and (1->3)- -D-Glucan, and Consequences of Delayed Antifungal Therapy

(2010) W. W. Hope et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Caspofungin first-line therapy for invasive aspergillosis in allogeneic hematopoietic stem cell transplant patients: an European Organisation for Research and Treatment of Cancer study

(2010) R Herbrecht et al.   BONE MARROW TRANSPLANTATION

European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3—2009 Update

(2010) J Maertens et al.   BONE MARROW TRANSPLANTATION

Aspergillusspecies intrinsically resistant to antifungal agents

(2010) Jan W. M. Van Der Linden et al.   MEDICAL MYCOLOGY

Combination Therapy in Treatment of Experimental Pulmonary Aspergillosis: In Vitro and In Vivo Correlations of the Concentration- and Dose- Dependent Interactions between Anidulafungin and Voriconazole by Bliss Independence Drug Interaction Analysis

(2009) V. Petraitis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy of Posaconazole against Three Clinical Aspergillus fumigatus Isolates with Mutations in the cyp51A Gene

(2009) E. Mavridou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Possible Environmental Origin of Resistance of Aspergillus fumigatus to Medical Triazoles

(2009) E. Snelders et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

An EORTC Phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patients

(2009) C. Viscoli et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Establishing In Vitro-In Vivo Correlations for Aspergillus fumigatus: the Challenge of Azoles versus Echinocandins

(2008) M. C. Arendrup et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism

(2008) Eveline Snelders et al.   PLOS MEDICINE