An electrochemical nanofilm sensor for determination of 1-hydroxypyrene using molecularly imprinted receptors

A novel electrochemical nanofilm sensor for 1-hydroxypyrene (1-OHP) was developed based on a molecular imprinted TiO2 gel matrix, which was prepared with Ti(O-n-Bu)(4) and 1-OHP using sol-gel technology. Cyclic voltammetry (CV) showed that guest binding on the non-imprinted sensor resulted in nearly the same current changes for all guest molecules, indicating non-specific binding onto the TiO2 gel matrix. In contrast, binding at the molecular imprinted sensor revealed that the selectivity for 1-OHP relative to structurally related guest molecules was estimated to be 1.8-6.7 times greater at 1 x 10(-9)M, reflecting its specific adsorption and binding capacity for the template molecule. (C) 2017 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.