Targeting Neutrophilic Inflammation Using Polymersome-Mediated Cellular Delivery

Purification of Nanoparticles by Size and Shape

(2016) James D. Robertson et al.   Scientific Reports

Defining the phenotype of neutrophils following reverse migration in zebrafish

(2015) Felix Ellett et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Great (Nuclear) Escape: New Insights into the Role of the Nuclear Egress Complex of Herpesviruses

(2015) Janna M. Bigalke et al.   JOURNAL OF VIROLOGY

pH-Sensitive Tubular Polymersomes: Formation and Applications in Cellular Delivery

(2014) James D. Robertson et al.   ACS Nano

Novel aspects of encapsulation and delivery using polymersomes

(2014) Léa Messager et al.   CURRENT OPINION IN PHARMACOLOGY

Activation of an Immunoregulatory and Antiviral Gene Expression Program in Poly(I:C)-Transfected Human Neutrophils

(2014) N. Tamassia et al.   JOURNAL OF IMMUNOLOGY

Polymersome-Mediated Delivery of Combination Anticancer Therapy to Head and Neck Cancer Cells: 2D and 3D in Vitro Evaluation

(2014) Helen E. Colley et al.   MOLECULAR PHARMACEUTICS

A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

(2014) A. L. Robertson et al.   Science Translational Medicine

Translocation of flexible polymersomes across pores at the nanoscale

(2014) Carla Pegoraro et al.   Biomaterials Science

Polymersome-mediated intracellular delivery of antibiotics to treat Porphyromonas gingivalis-infected oral epithelial cells

(2013) Kornchanok Wayakanon et al.   FASEB JOURNAL

Zebrafish as a model for the study of neutrophil biology

(2013) Katherine M. Henry et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Nile Blue-Based Nanosized pH Sensors for Simultaneous Far-Red and Near-Infrared Live Bioimaging

(2013) Jeppe Madsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of pH and Temperature on PMPC–PDPA Copolymer Self-Assembly

(2013) Russell T. Pearson et al.   MACROMOLECULES

Exploiting Endocytosis for Nanomedicines

(2013) A. Akinc et al.   Cold Spring Harbor Perspectives in Biology

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Cyclin-dependent kinases 7 and 9 specifically regulate neutrophil transcription and their inhibition drives apoptosis to promote resolution of inflammation

(2012) A E Leitch et al.   CELL DEATH AND DIFFERENTIATION

Endocytosis at the nanoscale

(2012) Irene Canton et al.   CHEMICAL SOCIETY REVIEWS

Fully synthetic polymer vesicles for intracellular delivery of antibodies in live cells

(2012) Irene Canton et al.   FASEB JOURNAL

Neutrophil Activation Is Attenuated by High-Density Lipoprotein and Apolipoprotein A-I in In Vitro and In Vivo Models of Inflammation

(2011) Andrew J. Murphy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Synthesis of Rhodamine 6G-Based Compounds for the ATRP Synthesis of Fluorescently Labeled Biocompatible Polymers

(2011) Jeppe Madsen et al.   BIOMACROMOLECULES

Activation of hypoxia-inducible factor-1  (Hif-1 ) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

(2011) P. M. Elks et al.   BLOOD

Phagosome dynamics during phagocytosis by neutrophils

(2011) Pontus Nordenfelt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation

(2011) David J. Wardle et al.   PLoS One

Wet Nanoscale Imaging and Testing of Polymersomes

(2011) Giuseppe Battaglia et al.   Small

Neutrophil clearance: when the party is over, clean-up begins

(2011) Donna L. Bratton et al.   TRENDS IN IMMUNOLOGY

Effects of particle size and ligand density on the kinetics of receptor-mediated endocytosis of nanoparticles

(2010) Hongyan Yuan et al.   APPLIED PHYSICS LETTERS

Neutrophils in rheumatoid arthritis: More than simple final effectors

(2010) R. Cascão et al.   AUTOIMMUNITY REVIEWS

The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation

(2010) Ranit Kedmi et al.   BIOMATERIALS

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

The cyclin-dependent kinase inhibitor R-roscovitine down-regulates Mcl-1 to override pro-inflammatory signalling and drive neutrophil apoptosis

(2010) Andrew E. Leitch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Critical Role for LTA4H in Limiting Chronic Pulmonary Neutrophilic Inflammation

(2010) R. J. Snelgrove et al.   SCIENCE

Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents

(2009) AE Leitch et al.   BRITISH JOURNAL OF PHARMACOLOGY

Size Effect on Cell Uptake in Well-Suspended, Uniform Mesoporous Silica Nanoparticles

(2009) Fang Lu et al.   Small

Controlling Cellular Uptake by Surface Chemistry, Size, and Surface Topology at the Nanoscale

(2009) Marzia Massignani et al.   Small

Physical approaches to biomaterial design

(2008) Samir Mitragotri et al.   NATURE MATERIALS

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery

(2008) Stéphane Berghmans et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Neutrophil Isolation Protocol

(2008) Hana Oh et al.   Jove-Journal of Visualized Experiments