Metabolic Reprogramming Commits Differentiation of Human CD27+IgD+B Cells to Plasmablasts or CD27−IgD−Cells

The PI3K pathway in B cell metabolism

(2016) Julia Jellusova et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells

(2016) Wing Y. Lam et al.   IMMUNITY

A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus

(2016) Madhvi Menon et al.   IMMUNITY

B-cell subsets, signaling and their roles in secretion of autoantibodies

(2016) S Iwata et al.   LUPUS

Metabolic regulation of natural killer cells: Figure 1

(2015) David K. Finlay   BIOCHEMICAL SOCIETY TRANSACTIONS

AMPK Helps T Cells Survive Nutrient Starvation

(2015) Kai Yang et al.   IMMUNITY

T cell metabolism drives immunity

(2015) Michael D. Buck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Glucose Oxidation Is Critical for CD4+T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus

(2015) Yiming Yin et al.   JOURNAL OF IMMUNOLOGY

Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases

(2015) Andras Perl   Nature Reviews Rheumatology

Regulation of T cells by mTOR: the known knowns and the known unknowns

(2015) Kristen N. Pollizzi et al.   TRENDS IN IMMUNOLOGY

Targeting CD8 T-Cell Metabolism in Transplantation

(2015) Michelle Yap et al.   Frontiers in Immunology

Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation

(2014) Masanori Matsumoto et al.   IMMUNITY

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

mTOR Activation Promotes Plasma Cell Differentiation and Bypasses XBP-1 for Immunoglobulin Secretion

(2014) Sandrine Benhamron et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular regulation of effector and memory T cell differentiation

(2014) John T Chang et al.   NATURE IMMUNOLOGY

AMPK: A metabolic switch for CD8+T-cell memory

(2013) Koichi Araki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

AMPKα1: A glucose sensor that controls CD8 T-cell memory

(2013) Julia Rolf et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming

(2013) Kai Yang et al.   IMMUNITY

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

(2013) Madhusudhanan Sukumar et al.   JOURNAL OF CLINICAL INVESTIGATION

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

(2013) Christian C. Dibble et al.   NATURE CELL BIOLOGY

Fueling Immunity: Insights into Metabolism and Lymphocyte Function

(2013) E. L. Pearce et al.   SCIENCE

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Metabolic switching and fuel choice during T-cell differentiation and memory development

(2012) Gerritje J. W. Windt et al.   IMMUNOLOGICAL REVIEWS

Amplification of Toll-like receptor–mediated signaling through spleen tyrosine kinase in human B-cell activation

(2012) Shigeru Iwata et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Comprehensive Review of Everolimus Clinical Reports

(2012) Cheryle Gurk-Turner et al.   TRANSPLANTATION

BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway

(2012) Egest J. Pone et al.   Nature Communications

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

(2011) R. D. Michalek et al.   JOURNAL OF IMMUNOLOGY

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

Cellular and molecular pathogenesis of systemic lupus erythematosus: lessons from animal models

(2011) Simanta Pathak et al.   ARTHRITIS RESEARCH & THERAPY

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis

(2010) Q. Huang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients

(2010) Beatriz Rodríguez-Bayona et al.   ARTHRITIS RESEARCH & THERAPY

mTOR phosphorylated at S2448 binds to raptor and rictor

(2009) M. Rosner et al.   AMINO ACIDS

Activation of Mammalian Target of Rapamycin Controls the Loss of TCR  in Lupus T Cells through HRES-1/Rab4-Regulated Lysosomal Degradation

(2009) D. R. Fernandez et al.   JOURNAL OF IMMUNOLOGY

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: Delineation by expression of CD27, IgD, and CD95

(2008) Annett M. Jacobi et al.   ARTHRITIS AND RHEUMATISM

Phenotypic and functional heterogeneity of human memory B cells

(2008) Iñaki Sanz et al.   SEMINARS IN IMMUNOLOGY