The Effect of Inhibitory Signals on the Priming of Drug Hapten–Specific T Cells That Express Distinct Vβ Receptors

Abacavir-Reactive Memory T Cells Are Present in Drug Naïve Individuals

(2015) Andrew Lucas et al.   PLoS One

Negative Regulation by PD-L1 during Drug-Specific Priming of IL-22-Secreting T Cells and the Influence of PD-1 on Effector T Cell Function

(2014) A. Gibson et al.   JOURNAL OF IMMUNOLOGY

Identification and frequency of circulating CD4+T lymphocytes specific to Benzylpenicillin in healthy donors

(2013) C. Nhim et al.   ALLERGY

Flow cytometric analysis of the CD4+ TCR Vβ repertoire in the peripheral blood of children with type 1 diabetes mellitus, systemic lupus erythematosus and age-matched healthy controls

(2013) Flora Tzifi et al.   BMC IMMUNOLOGY

A comparative study of flow cytometric T cell receptor Vβ repertoire and T cell receptor gene rearrangement in the diagnosis of large granular lymphocytic lymphoproliferation

(2013) Y.-C. Hsieh et al.   International Journal of Laboratory Hematology

Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing

(2012) M A Martin et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Development of In Vitro Culture Methods to Characterize Primary T-Cell Responses to Drugs

(2012) Lee Faulkner et al.   TOXICOLOGICAL SCIENCES

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

(2011) Tai-Ming Ko et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients

(2011) X. Meng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Stimulation of human T cells with sulfonamides and sulfonamide metabolites

(2010) J. Luis Castrejon et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiple Adduction Reactions of Nitroso Sulfamethoxazole with Cysteinyl Residues of Peptides and Proteins: Implications for Hapten Formation

(2009) Hayley E. Callan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Stable form of galectin-9, a Tim-3 ligand, inhibits contact hypersensitivity and psoriatic reactions: A potent therapeutic tool for Th1- and/or Th17-mediated skin inflammation

(2009) Haruna Niwa et al.   CLINICAL IMMUNOLOGY

T regulatory cells in contact hypersensitivity

(2009) Andrea Cavani   Current Opinion in Allergy and Clinical Immunology

TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

(2009) William D. Hastings et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Defective Regulatory T Cells In Patients with Severe Drug Eruptions: Timing of the Dysfunction Is Associated with the Pathological Phenotype and Outcome

(2009) R. Takahashi et al.   JOURNAL OF IMMUNOLOGY

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

TNF,LTA,HSPA1LandHLA-DRgene polymorphisms in HIV-positive patients with hypersensitivity to cotrimoxazole

(2009) Ana Alfirevic et al.   PHARMACOGENOMICS

Analysis of T cell receptor Vβ diversity in peripheral CD4+and CD8+T lymphocytes in patients with autoimmune thyroid diseases

(2008) M. Okajima et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY