The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+Thymocyte Selection

Thymic Emigration: When and How T Cells Leave Home

(2014) M. A. Weinreich et al.   JOURNAL OF IMMUNOLOGY

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling

(2014) Norihiro Nakamura et al.   NATURE

Commensal Bacteria Regulate Thymic Aire Expression

(2014) Akihito Nakajima et al.   PLoS One

Pathogen Sensing by Nucleotide-binding Oligomerization Domain-containing Protein 2 (NOD2) Is Mediated by Direct Binding to Muramyl Dipeptide and ATP

(2012) Jinyao Mo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease

(2011) Sarah A. Ingersoll et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Signaling in thymic selection

(2011) Nicholas RJ Gascoigne et al.   CURRENT OPINION IN IMMUNOLOGY

Crohn's disease: NOD2, autophagy and ER stress converge

(2011) T. Fritz et al.   GUT

Regulation of the Antimicrobial Response by NLR Proteins

(2011) Eran Elinav et al.   IMMUNITY

Nucleotide-binding and oligomerization domain-like receptors and retinoic acid inducible gene-like receptors in human tonsillar T lymphocytes

(2011) Terese Petterson et al.   IMMUNOLOGY

TLR4 Signaling via MyD88 and TRIF Differentially Shape the CD4+ T Cell Response to Porphyromonas gingivalis Hemagglutinin B

(2011) D. E. Gaddis et al.   JOURNAL OF IMMUNOLOGY

ATG16L1 and NOD2 Interact in an Autophagy-Dependent Antibacterial Pathway Implicated in Crohn's Disease Pathogenesis

(2010) Craig R. Homer et al.   GASTROENTEROLOGY

Postselection Thymocyte Maturation and Emigration Are Independent of IL-7 and ERK5

(2010) M. A. Weinreich et al.   JOURNAL OF IMMUNOLOGY

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

(2010) Jung-Hyun Park et al.   NATURE IMMUNOLOGY

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Direct Bacterial Killing In Vitro by Recombinant Nod2 Is Compromised by Crohn's Disease-Associated Mutations

(2010) Laurent-Herve Perez et al.   PLoS One

The distinct response of γδ T cells to the Nod2 agonist muramyl dipeptide

(2009) Hannah M.M. Kerns et al.   CELLULAR IMMUNOLOGY

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

(2009) S. Brand   GUT

pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling

(2009) Jooeun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiplexed labeling of samples with cell tracking dyes facilitates rapid and accurate internally controlled calcium flux measurement by flow cytometry

(2009) Guo Fu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Clathrin- and Dynamin-Dependent Endocytic Pathway Regulates Muramyl Dipeptide Internalization and NOD2 Activation

(2009) N. Marina-Garcia et al.   JOURNAL OF IMMUNOLOGY

TLR2 Engagement on CD8 T Cells Enables Generation of Functional Memory Cells in Response to a Suboptimal TCR Signal

(2009) B. C. Mercier et al.   JOURNAL OF IMMUNOLOGY

A function for AAMP in Nod2-mediated NF-κB activation

(2009) H. Bielig et al.   MOLECULAR IMMUNOLOGY

T cell–intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii

(2009) Michael H Shaw et al.   NATURE IMMUNOLOGY

Nod2 is required for the regulation of commensal microbiota in the intestine

(2009) T. Petnicki-Ocwieja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIP2 Is Required for NOD Signaling But Not for Th1 Cell Differentiation and Cellular Allograft Rejection

(2008) T. Fairhead et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Effective T-cell immune responses in the absence of the serine/threonine kinase RIP2

(2008) Chiara Nembrini et al.   MICROBES AND INFECTION

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

(2008) Djahida Bouskra et al.   NATURE

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY

Lineage Diversion of T Cell Receptor Transgenic Thymocytes Revealed by Lineage Fate Mapping

(2008) Takeshi Egawa et al.   PLoS One

RIP2 contributes to Nod signaling but is not essential for T cell proliferation, T helper differentiation or TLR responses

(2007) Håkan T. L. Hall et al.   EUROPEAN JOURNAL OF IMMUNOLOGY