Inflammasome and Fas-Mediated IL-1β Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells

(2016) Renu Jain et al.   IMMUNITY

T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis

(2016) Bradley N Martin et al.   NATURE IMMUNOLOGY

Demethylation of theRORC2andIL17Ain Human CD4+T Lymphocytes Defines Th17 Origin of Nonclassic Th1 Cells

(2015) Alessio Mazzoni et al.   JOURNAL OF IMMUNOLOGY

Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

(2015) S. Okada et al.   SCIENCE

Caspases as the Key Effectors of Inflammatory Responses Against Bacterial Infection

(2014) Ryosuke Uchiyama et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

The adaptor ASC exacerbates lethalListeria monocytogenesinfection by mediating IL-18 production in an inflammasome-dependent and -independent manner

(2014) Kohsuke Tsuchiya et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mutation in the Fas Pathway Impairs CD8+ T Cell Memory

(2014) R. Dudani et al.   JOURNAL OF IMMUNOLOGY

IL-17A Produced by    T Cells Plays a Critical Role in Innate Immunity against Listeria monocytogenes Infection in the Liver

(2014) S. Hamada et al.   JOURNAL OF IMMUNOLOGY

IL-1  Promotes the Differentiation of Polyfunctional Human CCR6+CXCR3+ Th1/17 Cells That Are Specific for Pathogenic and Commensal Microbes

(2014) T. Duhen et al.   JOURNAL OF IMMUNOLOGY

Microbial Sensing by Toll-Like Receptors and Intracellular Nucleic Acid Sensors

(2014) Surya Pandey et al.   Cold Spring Harbor Perspectives in Biology

The Inflammasome and Its Regulation

(2013) Kohsuke Tsuchiya et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Lack ofMycobacterium tuberculosis-specific interleukin-17A-producing CD4+T cells in active disease

(2013) Matthieu Perreau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Fas-Mediated Inflammatory Response in Listeria monocytogenes Infection

(2013) R. Uchiyama et al.   JOURNAL OF IMMUNOLOGY

Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3+CCR6+ Th1 Subset

(2013) Cecilia S. Lindestam Arlehamn et al.   PLoS Pathogens

Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells

(2012) Laura Maggi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferon-gamma-mediated tissue factor expression contributes to T-cell-mediated hepatitis through induction of hypercoagulation in mice

(2012) Junko Kato et al.   HEPATOLOGY

Cutting Edge: FAS (CD95) Mediates Noncanonical IL-1  and IL-18 Maturation via Caspase-8 in an RIP3-Independent Manner

(2012) L. Bossaller et al.   JOURNAL OF IMMUNOLOGY

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Defining the human T helper 17 cell phenotype

(2012) Francesco Annunziato et al.   TRENDS IN IMMUNOLOGY

Functional Specialization of Interleukin-17 Family Members

(2011) Yoichiro Iwakura et al.   IMMUNITY

Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR9

(2010) Cevayir Coban et al.   Cell Host & Microbe

Listeria monocytogenes Triggers AIM2-Mediated Pyroptosis upon Infrequent Bacteriolysis in the Macrophage Cytosol

(2010) John-Demian Sauer et al.   Cell Host & Microbe

The Receptor SIGIRR Suppresses Th17 Cell Proliferation via Inhibition of the Interleukin-1 Receptor Pathway and mTOR Kinase Activation

(2010) Muhammet F. Gulen et al.   IMMUNITY

PD-1-PD-L1 pathway impairs Th1 immune response in the late stage of infection with Mycobacterium bovis bacillus Calmette-Guerin

(2010) S. Sakai et al.   INTERNATIONAL IMMUNOLOGY

Involvement of Absent in Melanoma 2 in Inflammasome Activation in Macrophages Infected with Listeria monocytogenes

(2010) K. Tsuchiya et al.   JOURNAL OF IMMUNOLOGY

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells

(2009) Natalia Martin-Orozco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling

(2009) Yeonseok Chung et al.   IMMUNITY

The RD1 Locus in the Mycobacterium tuberculosis Genome Contributes to Activation of Caspase-1 via Induction of Potassium Ion Efflux in Infected Macrophages

(2009) T. Kurenuma et al.   INFECTION AND IMMUNITY

Listeria monocytogenes-Infected Human Peripheral Blood Mononuclear Cells Produce IL-1 , Depending on Listeriolysin O and NLRP3

(2009) K. Meixenberger et al.   JOURNAL OF IMMUNOLOGY

IL-23 Is Required for Protection against Systemic Infection with Listeria monocytogenes

(2009) K. D. Meeks et al.   JOURNAL OF IMMUNOLOGY

ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection

(2008) Ingrid C. Koo et al.   CELLULAR MICROBIOLOGY

Importance of murine Vδ1+γδ T cells expressing interferon-γ and interleukin-17A in innate protection againstListeria monocytogenesinfection

(2008) Satoru Hamada et al.   IMMUNOLOGY

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

(2008) Dror Luger et al.   JOURNAL OF EXPERIMENTAL MEDICINE