Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism

Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer

(2017) Dyah L. Dewi et al.   OncoImmunology

Activated human B cells induce inflammatory fibroblasts with cartilage-destructive properties and become functionally suppressed in return

(2015) Hannah Störch et al.   ANNALS OF THE RHEUMATIC DISEASES

Downregulation of Tryptophan-related Metabolomic Profile in Rheumatoid Arthritis Synovial Fluid

(2015) K. Y. Kang et al.   JOURNAL OF RHEUMATOLOGY

T cell subsets and their role in the pathogenesis of rheumatic disease

(2014) Alison M. Gizinski et al.   CURRENT OPINION IN RHEUMATOLOGY

The Enzyme Cyp26b1 Mediates Inhibition of Mast Cell Activation by Fibroblasts to Maintain Skin-Barrier Homeostasis

(2014) Yosuke Kurashima et al.   IMMUNITY

Chronically Inflamed Human Tissues Are Infiltrated by Highly Differentiated Th17 Lymphocytes

(2014) J. Pene et al.   JOURNAL OF IMMUNOLOGY

Modulation of TNF-Induced Macrophage Polarization by Synovial Fibroblasts

(2014) Laura T. Donlin et al.   JOURNAL OF IMMUNOLOGY

Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell targets

(2014) D. E. Furst et al.   RHEUMATOLOGY

Inhibition of Spermidine/Spermine N1-Acetyltransferase Activity: A New Therapeutic Concept in Rheumatoid Arthritis

(2014) Michel Neidhart et al.   Arthritis & Rheumatology

Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis

(2013) Giulia Benedetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Synovial Fibroblasts Directly Induce Th17 Pathogenicity via the Cyclooxygenase/Prostaglandin E2 Pathway, Independent of IL-23

(2013) S. M. J. Paulissen et al.   JOURNAL OF IMMUNOLOGY

Functional niche of inflamed synovium for Th17-cell expansion and activation in rheumatoid arthritis: Implication to clinical therapeutics

(2012) Weijia Dong et al.   AUTOIMMUNITY REVIEWS

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

How mesenchymal stem cells interact with tissue immune responses

(2012) Yufang Shi et al.   TRENDS IN IMMUNOLOGY

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

(2012) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Serum and synovial fluid levels of interleukin-17 in correlation with disease activity in patients with RA

(2011) Siham Ali Metawi et al.   CLINICAL RHEUMATOLOGY

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Role of Th17 cells in human autoimmune arthritis

(2010) Jan Leipe et al.   ARTHRITIS AND RHEUMATISM

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Human Bone Marrow Stromal Cells and Skin Fibroblasts Inhibit Natural Killer Cell Proliferation and Cytotoxic Activity

(2010) Amandine Pradier et al.   CELL TRANSPLANTATION

Local Expression of Indoleamine 2,3 Dioxygenase in Syngeneic Fibroblasts Significantly Prolongs Survival of an Engineered Three-Dimensional Islet Allograft

(2010) R. B. Jalili et al.   DIABETES

Amelioration of Rat Collagen-Induced Arthritis Through CD4+ T Cells Apoptosis and Synovial Interleukin-17 Reduction by Indoleamine 2,3-Dioxygenase Gene Therapy

(2010) Shih-Yao Chen et al.   HUMAN GENE THERAPY

Human Fibroblasts Share Immunosuppressive Properties with Bone Marrow Mesenchymal Stem Cells

(2010) Sandrine Cappellesso-Fleury et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Indoleamine 2,3 dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis

(2009) Gabriel Criado et al.   ARTHRITIS AND RHEUMATISM

DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

(2009) Emmanuel Karouzakis et al.   ARTHRITIS AND RHEUMATISM

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells

(2009) B. Baban et al.   JOURNAL OF IMMUNOLOGY

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

PD-1 Ligand Expression by Human Colonic Myofibroblasts/Fibroblasts Regulates CD4+ T-Cell Activity

(2008) Irina V. Pinchuk et al.   GASTROENTEROLOGY

TH-17 cells in rheumatoid arthritis

(2008) Shiva Shahrara et al.   ARTHRITIS RESEARCH & THERAPY