Neurodegeneration Enhances the Development of Arthritis

Innate Lymphocyte/Ly6C hi Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance

(2016) Huizhong Xiong et al.   CELL

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

(2016) Yaming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise

(2015) M. S. Brook et al.   Acta Physiologica

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Invited review: Frontotemporal dementia caused bymicrotubule-associated protein taugene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

(2015) Bernardino Ghetti et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Systemic Inflammation and the Brain: Novel Roles of Genetic, Molecular, and Environmental Cues as Drivers of Neurodegeneration

(2015) Roman Sankowski et al.   Frontiers in Cellular Neuroscience

Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody

(2015) Wenjie Luo et al.   Scientific Reports

The Critical Need to Promote Research of Aging and Aging-related Diseases to Improve Health and Longevity of the Elderly Population

(2015) Kunlin Jin et al.   Aging and Disease

Two Novel α7 Nicotinic Acetylcholine Receptor Ligands: In Vitro Properties and Their Efficacy in Collagen-Induced Arthritis in Mice

(2015) Marjolein A. van Maanen et al.   PLoS One

Role of CCR2 in Inflammatory Conditions of the Central Nervous System

(2014) Hannah X Chu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Alterations in Tight Junction Protein and IgG Permeability Accompany Leukocyte Extravasation Across the Choroid Plexus During Neuroinflammation

(2014) Bandana Shrestha et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

No Evidence of Pathogenic Involvement of Cathelicidins in Patient Cohorts and Mouse Models of Lupus and Arthritis

(2014) D. Kienhöfer et al.   PLoS One

Economic and social implications of aging societies

(2014) S. Harper   SCIENCE

Combined Inhibition of Tumor Necrosis Factor α and Interleukin-17 As a Therapeutic Opportunity in Rheumatoid Arthritis: Development and Characterization of a Novel Bispecific Antibody

(2014) Jens A. A. Fischer et al.   Arthritis & Rheumatology

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies

(2013) Antonella Caccamo et al.   AGING CELL

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice

(2013) Steven Biesmans et al.   MEDIATORS OF INFLAMMATION

Lymphocyte-derived ACh regulates local innate but not adaptive immunity

(2013) Colin Reardon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of brain functional magnetic resonance activity with response to tumor necrosis factor inhibition in rheumatoid arthritis

(2012) Juergen Rech et al.   ARTHRITIS AND RHEUMATISM

Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach

(2012) Nadege Zommer et al.   Current Alzheimer Research

Neural reflexes in inflammation and immunity

(2012) Ulf Andersson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline

(2012) Johannes vom Berg et al.   NATURE MEDICINE

Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice

(2011) Sun Park et al.   BMC NEUROSCIENCE

Osteoarthritis: an update with relevance for clinical practice

(2011) Johannes WJ Bijlsma et al.   LANCET

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

Increased Intrathecal High-Avidity Anti-Tau Antibodies in Patients with Multiple Sclerosis

(2011) Lenka Fialová et al.   PLoS One

Blockade of TNF-α rapidly inhibits pain responses in the central nervous system

(2011) Andreas Hess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of Brain-infiltrating Leukocytes

(2011) Reghann G. LaFrance-Corey et al.   Jove-Journal of Visualized Experiments

Isolation of Brain and Spinal Cord Mononuclear Cells Using Percoll Gradients

(2011) Paula A. Pino et al.   Jove-Journal of Visualized Experiments

Evaluation of therapeutic targets in animal models of arthritis: How does it relate to rheumatoid arthritis?

(2010) Lisette Bevaart et al.   ARTHRITIS AND RHEUMATISM

Older age of rheumatoid arthritis onset is associated with higher activation status of peripheral blood CD4+ T cells and disease activity

(2010) J. Pawłowska et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS

(2010) Marco Prinz et al.   JOURNAL OF NEUROIMMUNOLOGY

Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model

(2010) A. Boutajangout et al.   JOURNAL OF NEUROSCIENCE

Myeloid cell subsets dynamic during progression of mouse collagen-induced arthritis

(2010) J Presumey et al.   Journal of Translational Medicine

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

Genome-Wide Comparison between IL-17A- and IL-17F-Induced Effects in Human Rheumatoid Arthritis Synoviocytes

(2009) S. Zrioual et al.   JOURNAL OF IMMUNOLOGY

Evidence for a common pathway linking neurodegenerative diseases

(2009) Joshua M Shulman et al.   NATURE GENETICS

Monocyte-Mediated Defense Against Microbial Pathogens

(2008) Natalya V. Serbina et al.   Annual Review of Immunology

Proteasome inhibition drastically but reversibly impairs murine lymphocyte development

(2008) D Maseda et al.   CELL DEATH AND DIFFERENTIATION

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE