Immunomodulatory Molecule IRAK-M Balances Macrophage Polarization and Determines Macrophage Responses during Renal Fibrosis

IRAK-M Promotes Alternative Macrophage Activation and Fibroproliferation in Bleomycin-Induced Lung Injury

(2015) Megan N. Ballinger et al.   JOURNAL OF IMMUNOLOGY

The role of Interleukin Receptor Associated Kinase (IRAK)-M in regulation of myofibroblast phenotype in vitro, and in an experimental model of non-reperfused myocardial infarction

(2015) Amit Saxena et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Macrophages Regulate Renal Fibrosis Through Modulating TGFβ Superfamily Signaling

(2014) Bing Shen et al.   INFLAMMATION

Association Between Gene Polymorphisms of IRAK-M and the Susceptibility of Sepsis

(2013) Gao-hong Dong et al.   INFLAMMATION

Macrophage Phenotype Controls Long-Term AKI Outcomes--Kidney Regeneration versus Atrophy

(2013) M. Lech et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

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(2013) Tarcio Braga et al.   MOLECULAR MEDICINE

TLR-2/TLR-4 TREM-1 Signaling Pathway Is Dispensable in Inflammatory Myeloid Cells during Sterile Kidney Injury

(2013) Gabriela Campanholle et al.   PLoS One

Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages

(2012) Huy A. Nguyen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation of wound healing and organ fibrosis by toll-like receptors

(2012) Peter Huebener et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Macrophages and fibrosis: How resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair

(2012) Maciej Lech et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus

(2011) M. Lech et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-13 dampens human airway epithelial innate immunity through induction of IL-1 receptor–associated kinase M

(2011) Qun Wu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1  Secretion through the NLRP3 Inflammasome In Vitro

(2011) B. Pazar et al.   JOURNAL OF IMMUNOLOGY

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growth

(2011) T J Standiford et al.   ONCOGENE

Toll-Like Receptor Signaling and SIGIRR in Renal Fibrosis upon Unilateral Ureteral Obstruction

(2011) Veronika Skuginna et al.   PLoS One

Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice

(2010) M. Lech et al.   INTERNATIONAL IMMUNOLOGY

Mechanisms of Tubulointerstitial Fibrosis

(2010) M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prevention and Transplantation in Chronic Kidney Disease: What Is Achievable in Emerging Countries?

(2010) Veerle P. Persy et al.   NEPHRON CLINICAL PRACTICE

In Vivo Lipopolysaccharide Exposure of Human Blood Leukocytes Induces Cross-Tolerance to Multiple TLR Ligands

(2009) A. F. de Vos et al.   JOURNAL OF IMMUNOLOGY

Effects of Liposome Clodronate on Renal Leukocyte Populations and Renal Fibrosis in Murine Obstructive Nephropathy

(2009) Koichiro Kitamoto et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

New Insights into Epithelial-Mesenchymal Transition in Kidney Fibrosis

(2009) Y. Liu   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

(2009) Robert L. Chevalier et al.   KIDNEY INTERNATIONAL

The Role of Toll-Like Receptor 2 in Inflammation and Fibrosis during Progressive Renal Injury

(2009) Jaklien C. Leemans et al.   PLoS One

When Signaling Pathways Collide: Positive and Negative Regulation of Toll-like Receptor Signal Transduction

(2008) Luke A.J. O'Neill   IMMUNITY

Innate immunity to pathogens: diversity in receptors for microbial recognition

(2008) Shizuo Akira   IMMUNOLOGICAL REVIEWS

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE