Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+T Cell Expression of IL-22 and Mucosal Release of Calprotectin

Unconventional Human T Cells Accumulate at the Site of Infection in Response to Microbial Ligands and Induce Local Tissue Remodeling

(2016) Anna Rita Liuzzi et al.   JOURNAL OF IMMUNOLOGY

Evidence of innate lymphoid cell redundancy in humans

(2016) Frédéric Vély et al.   NATURE IMMUNOLOGY

Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

(2016) R. Duffin et al.   SCIENCE

A pathogenic role for T cell–derived IL-22BP in inflammatory bowel disease

(2016) Penelope Pelczar et al.   SCIENCE

Interleukin-22: Immunobiology and Pathology

(2015) Jarrod A. Dudakov et al.   Annual Review of Immunology

Human Vγ9/Vδ2 T cells: Innate adaptors of the immune system

(2015) Christopher J. Tyler et al.   CELLULAR IMMUNOLOGY

Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability

(2015) Jacob S. Lee et al.   IMMUNITY

OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response

(2015) Clément Jacquemin et al.   IMMUNITY

Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease

(2015) Neil E. McCarthy et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of the intestinal cytokine microenvironment in shaping the intraepithelial lymphocyte repertoire

(2015) Yuan Qiu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Complementarity and redundancy of IL-22-producing innate lymphoid cells

(2015) Lucille C Rankin et al.   NATURE IMMUNOLOGY

Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen

(2014) Tu Anh N. Pham et al.   Cell Host & Microbe

A pro-inflammatory role for Th22 cells inHelicobacter pylori-associated gastritis

(2014) Yuan Zhuang et al.   GUT

The Cytokine IL-22 Promotes Pathogen Colonization by Suppressing Related Commensal Bacteria

(2014) Judith Behnsen et al.   IMMUNITY

The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human Vγ9Vδ2 T Cells

(2014) Andrew Sandstrom et al.   IMMUNITY

Human Gut Dendritic Cells Drive Aberrant Gut-specific T-cell Responses in Ulcerative Colitis, Characterized by Increased IL-4 Production and Loss of IL-22 and IFNγ

(2014) Elizabeth R. Mann et al.   INFLAMMATORY BOWEL DISEASES

Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness

(2014) Joseph M. Pickard et al.   NATURE

Proinflammatory V 2+ T Cells Populate the Human Intestinal Mucosa and Enhance IFN-  Production by Colonic    T Cells

(2013) N. E. McCarthy et al.   JOURNAL OF IMMUNOLOGY

IL-22-producing CD4+ cells are depleted in actively inflamed colitis tissue

(2013) J M Leung et al.   Mucosal Immunology

Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut

(2012) Janet Z. Liu et al.   Cell Host & Microbe

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

(2012) Wolfgang Hueber et al.   GUT

The CD27 and CD70 Costimulatory Pathway Inhibits Effector Function of T Helper 17 Cells and Attenuates Associated Autoimmunity

(2012) Jonathan M. Coquet et al.   IMMUNITY

Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunity

(2011) Caspar Ohnmacht et al.   CELLULAR MICROBIOLOGY

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

(2011) Hélène Bour-Jordan et al.   IMMUNOLOGICAL REVIEWS

Identification of a Novel Proinflammatory Human Skin-Homing V 9V 2 T Cell Subset with a Potential Role in Psoriasis

(2011) U. Laggner et al.   JOURNAL OF IMMUNOLOGY

Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt+ Innate Lymphocytes

(2010) Cedric Vonarbourg et al.   IMMUNITY

IL-22+ CD4+ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient

(2010) M. J. Broadhurst et al.   Science Translational Medicine

γδ T Cells and the Lymphoid Stress-Surveillance Response

(2009) Adrian C. Hayday   IMMUNITY

IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells

(2009) Kristine E. Nograles et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling

(2009) Stefanie Eyerich et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production

(2009) H. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

(2008) Brian D. Corbin et al.   SCIENCE