IL-15 Complexes Induce Migration of Resting Memory CD8 T Cells into Mucosal Tissues

Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection

(2016) Sama Adnan et al.   PLoS Pathogens

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation

(2015) Kristen N. Pollizzi et al.   JOURNAL OF CLINICAL INVESTIGATION

Soluble Interleukin-15 Complexes Are Generated In Vivo by Type I Interferon Dependent and Independent Pathways

(2015) Scott M. Anthony et al.   PLoS One

The Transcription Factor T-bet Is Induced by IL-15 and Thymic Agonist Selection and Controls CD8αα+ Intraepithelial Lymphocyte Development

(2014) Christoph S.N. Klose et al.   IMMUNITY

CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection

(2014) Brian J. Laidlaw et al.   IMMUNITY

FOXO1 Regulates L-Selectin and a Network of Human T Cell Homing Molecules Downstream of Phosphatidylinositol 3-Kinase

(2014) S. Fabre et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Generation of Effector Cells That Localize to Mucosal Tissues and Form Resident Memory CD8 T Cells Is Controlled by mTOR

(2014) Ryan T. Sowell et al.   JOURNAL OF IMMUNOLOGY

The Chemokine Receptor CXCR6 Is Required for the Maintenance of Liver Memory CD8+ T Cells Specific for Infectious Pathogens

(2014) Sze-Wah Tse et al.   JOURNAL OF INFECTIOUS DISEASES

The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells

(2014) Antoine Marçais et al.   NATURE IMMUNOLOGY

Intravascular staining for discrimination of vascular and tissue leukocytes

(2014) Kristin G Anderson et al.   Nature Protocols

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

(2014) N. Iijima et al.   SCIENCE

Transforming Growth Factor-β Signaling Controls the Formation and Maintenance of Gut-Resident Memory T Cells by Regulating Migration and Retention

(2013) Nu Zhang et al.   IMMUNITY

The Transcription Factor Foxo1 Controls Central-Memory CD8+ T Cell Responses to Infection

(2013) Myoungjoo V. Kim et al.   IMMUNITY

Differentiation of CD8 memory T cells depends on Foxo1

(2013) Rodrigo Hess Michelini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

FoxO1 Controls Effector-to-Memory Transition and Maintenance of Functional CD8 T Cell Memory

(2013) M. M. Tejera et al.   JOURNAL OF IMMUNOLOGY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

The Impact of KLF2 Modulation on the Transcriptional Program and Function of CD8 T Cells

(2013) Gavin C. Preston et al.   PLoS One

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation

(2012) Rajesh R. Rao et al.   IMMUNITY

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

(2012) L. K. Mackay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Interleukin-21- Interleukin-10-STAT3 Pathway Is Critical for Functional Maturation of Memory CD8+ T Cells

(2011) Weiguo Cui et al.   IMMUNITY

A Central Role for mTOR Kinase in Homeostatic Proliferation Induced CD8+ T Cell Memory and Tumor Immunity

(2011) Qingsheng Li et al.   IMMUNITY

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

(2011) Gerritje J.W. van der Windt et al.   IMMUNITY

The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns

(2011) Kenneth J. Oestreich et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: IL-15-Independent Maintenance of Mucosally Generated Memory CD8 T Cells

(2011) K. C. Verbist et al.   JOURNAL OF IMMUNOLOGY

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor

(2010) Chia-Chen Chen et al.   DEVELOPMENTAL CELL

The mTOR Kinase Determines Effector versus Memory CD8 + T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

(2010) Rajesh R. Rao et al.   IMMUNITY

Dynamic T cell migration program provides resident memory within intestinal epithelium

(2010) David Masopust et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential Localization of Effector and Memory CD8 T Cell Subsets in Lymphoid Organs during Acute Viral Infection

(2010) Y. W. Jung et al.   JOURNAL OF IMMUNOLOGY

Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence

(2010) L. M. Wakim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1

(2009) Jingxiang Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Macrophage- and Dendritic-Cell-Derived Interleukin-15 Receptor Alpha Supports Homeostasis of Distinct CD8+ T Cell Subsets

(2009) Erwan Mortier et al.   IMMUNITY

Opposing Effects of TGF-β and IL-15 Cytokines Control the Number of Short-Lived Effector CD8+ T Cells

(2009) Shomyseh Sanjabi et al.   IMMUNITY

Trans-Presentation of IL-15 by Intestinal Epithelial Cells Drives Development of CD8   IELs

(2009) L. J. Ma et al.   JOURNAL OF IMMUNOLOGY

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor

(2009) Yann M Kerdiles et al.   NATURE IMMUNOLOGY

Dendritic cells drive memory CD8 T-cell homeostasis via IL-15 transpresentation

(2008) S. W. Stonier et al.   BLOOD

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

(2008) Linda V Sinclair et al.   NATURE IMMUNOLOGY