Journal
JOURNAL OF HYPERTENSION
Volume 35, Issue 9, Pages 1808-1815Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/HJH.0000000000001399
Keywords
antihypertensive medication; blood pressure; blood pressure control; double product; heart rate; Japan Arteriosclerosis Longitudinal Study; population science
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Funding
- Japan Arteriosclerosis Prevention Fund (JAPF)
- Ministry of Education, Culture, Sports, Science and Technology, Japan [16H05263, 16KT0009]
- Grants-in-Aid for Scientific Research [17H04123, 16H05263, 16KT0009] Funding Source: KAKEN
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Objective: To identify the characteristics of blood pressure (BP), heart rate (HR), and double product in a Japanese population sample. Methods: We pooled individual records from 1999 to 2005 for 111 007 participants in 25 community-based cohorts and seven worksite-based cohorts. The data were analyzed to provide information on BP, HR, and double product according to age-sex groups and use of antihypertensive medication. Results: Average BP was 130/77mmHg among men and women combined. Among untreated individuals, SBP increased with age, whereas DBP reached a ceiling around the age of 60 years. The average SBP of treated participants was around 140 mmHg, irrespective of age, whereas DBP decreased linearly with age, and 56.4% of treated participants had a BP of 140/90mmHg or over. HR did not differ across age groups or treatment status. The double product, also called the rate-pressure product, calculated by multiplying the SBP and the HR, increased with age among untreated individuals, whereas it first decreased and then increased with age among treated individuals. Conclusion: Based on these collaborative data, insufficient BP control in Japan, where the average life expectancy is the longest in the world, was seen.
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