Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

(2016) Jin Zhang et al.   Cell Stem Cell

Cancer metabolism at a glance

(2016) Alexei Vazquez et al.   JOURNAL OF CELL SCIENCE

Preleukemia: one name, many meanings

(2016) H P Koeffler et al.   LEUKEMIA

Cancer stem cell metabolism: a potential target for cancer therapy

(2016) Abhijeet Deshmukh et al.   Molecular Cancer

LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell–like Transcriptional Program in AML

(2016) Jianbiao Zhou et al.   MOLECULAR CANCER RESEARCH

Overexpression of the PSAT1 Gene in Nasopharyngeal Carcinoma Is an Indicator of Poor Prognosis

(2016) Kuang-Ming Liao et al.   Journal of Cancer

LIN28Boverexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

(2015) Hetty H. Helsmoortel et al.   BLOOD

Aberrant regulation of the LIN28A/LIN28B and let-7 loop in human malignant tumors and its effects on the hallmarks of cancer

(2015) Tianzhen Wang et al.   Molecular Cancer

Lin28b Is Sufficient to Drive Liver Cancer and Necessary for Its Maintenance in Murine Models

(2014) Liem H. Nguyen et al.   CANCER CELL

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC

(2014) Maroof Alam et al.   MOLECULAR CANCER RESEARCH

Identification and targeting leukemia stem cells: The path to the cure for acute myeloid leukemia

(2014) Jianbiao Zhou   World Journal of Stem Cells

LIN28/LIN28B: An emerging oncogenic driver in cancer stem cells

(2013) Jianbiao Zhou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A clinically relevant population of leukemic CD34+CD38- cells in acute myeloid leukemia

(2012) J. M. Gerber et al.   BLOOD

Distinct microRNA Expression Profiles in Prostate Cancer Stem/Progenitor Cells and Tumor-Suppressive Functions of let-7

(2012) C. Liu et al.   CANCER RESEARCH

Cancer metabolism: Key players in metabolic reprogramming

(2012) Tomoyoshi Soga   CANCER SCIENCE

Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

(2012) Wen Cai Zhang et al.   CELL

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

(2012) Jessica L. Bell et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

(2012) Jan J Molenaar et al.   NATURE GENETICS

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML

(2011) J. Zhou et al.   BLOOD

IMP-1 Displays Cross-Talk with K-Ras and Modulates Colon Cancer Cell Survival through the Novel Proapoptotic Protein CYFIP2

(2011) P. S. Mongroo et al.   CANCER RESEARCH

LIN28B Promotes Colon Cancer Progression and Metastasis

(2011) C. E. King et al.   CANCER RESEARCH

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

(2011) Richard Possemato et al.   NATURE

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

(2011) Jason W Locasale et al.   NATURE GENETICS

Genome-Wide Studies Reveal That Lin28 Enhances the Translation of Genes Important for Growth and Survival of Human Embryonic Stem Cells

(2011) Shuping Peng et al.   STEM CELLS

Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells

(2010) X. Yang et al.   CANCER RESEARCH

Lin28: A MicroRNA Regulator with a Macro Role

(2010) Srinivas R. Viswanathan et al.   CELL

Microrna let-7: an emerging next-generation cancer therapeutic

(2010) D. Barh et al.   Current Oncology

Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights

(2010) Xiongpeng Zhu et al.   Journal of Hematology & Oncology

A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers

(2009) B. C. Christensen et al.   CARCINOGENESIS

ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside

(2009) Jianbiao Zhou et al.   Journal of Hematology & Oncology

Molecular prognostic markers for adult acute myeloid leukemia with normal cytogenetics

(2009) Tara K Gregory et al.   Journal of Hematology & Oncology

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

(2009) T.-C. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

let-7 microRNAs in development, stem cells and cancer

(2008) Ingo Büssing et al.   TRENDS IN MOLECULAR MEDICINE